271 Results for "

CD4

" in MedChemExpress (MCE) Product Catalog:
Products (271)

271 Results for "CD4" in MCE Product Catalog:

Cat. No.: HY-B0202S4
Synonyms: SR-47436-13C,d4; BMS-186295-13C,d4
Irbesartan- 13C,d4 (SR-47436- 13C,d4; BMS-186295- 13C,d4) is 13C-labeled Irbesartan (HY-B0202) .
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Cat. No.: HY-154771S
Clopidogrelat- 13C,d4 is 13C and deuterated labeled Clopidogrelat.
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Cat. No.: HY-W654058
L-Arginine- 13C,d4 (dihydrochloride) is 13C labeled L-Arginine (dihydrochloride) .
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Cat. No.: HY-B1473S2
CAS No.: 1269486-67-0
Synonyms: 5-Hydroxytryptamine-13C,D4; 5-HT-13C,D4
Serotonin- 13C,D4 (5-Hydroxytryptamine-13C,D4) is a 13C- and deuterated labeled Serotonin (HY-B1473A). Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM .
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Cat. No.: HY-W005355S8
CAS No.: 2483824-49-1
Sodium 2-oxobutanoate- 13C,d4 is the deuterium and 13C labeled Sodium 2-oxobutanoate .
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Cat. No.: HY-117160S2
4-trans-Hydroxy glibenclamide- 13C,d4 is 13C and deuterated labeled 4-trans-Hydroxy glibenclamide.
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Cat. No.: HY-Y0781S5
CAS No.: 2244703-17-9
Synonyms: Acetylformic acid-13C,d4
Pyruvic acid- 13C,d4 is the deuterium and 13C labeled Pyruvic acid . Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats .
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Cat. No.: HY-P990742
CAS No.: 2762499-30-7
Synonyms: TJ-CD4B; ABL111; TJ033721

Target:  

TNF Receptor Claudin

Research Areas:  

Inflammation/Immunology Cancer

Givastomig (ABL111, TJ033721) is a bispecific antibody (BsAb) inhibitor. Givastomig can specifically binds to Claudin18.2 (CLDN 18.2) on the surface of cancer cells and 4-1BB (CD137, TNFRSF9) on the surface of activated T cells and natural killer (NK) cells. Givastomig is engineered to contain a single Fc-domain mutation (asparagine to alanine) to eliminate Fc-effector function. Givastomig-bound cell lines expressing a range of CLDN18.2 levels with high affinity and induced 4-1BB activation only in the context of CLDN18.2 binding. Givastomig can be used for the study of colon carcinoma .
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Cat. No.: HY-W006057AS14
CAS No.: 1202865-40-4
Sodium 3-methyl-2-oxobutanoate- 13C,d4 is the deuterium and 13C labeled Sodium 3-methyl-2-oxobutanoate . Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli [4].
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Cat. No.: HY-W013677S1
CAS No.: 285977-82-4
4-Fluorobenzoic acid- 13C,d4 is the 13C- and deuterium labeled 4-Fluorobenzoic acid (HY-W013677). 4-Fluorobenzoic acid is a drug intermediate that can be used to synthesize a series of hydrazone derivatives with antituberculosis activity and Schiff bases with DPPH radical scavenging activity .
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Cat. No.: HY-B0094S3
Synonyms: Qinghaosu-13C,d4; NSC 369397-13C,d4
Artemisinin- 13C,d4 is 13C and deuterated labeled Artemisinin (HY-B0094). Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .
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