390 Results for "

glucuronide

" in MedChemExpress (MCE) Product Catalog:
Products (390)

390 Results for "glucuronide" in MCE Product Catalog:

Cat. No.: HY-167927S
Mycophenolic Acid-d3 Acyl-Beta-D-glucuronide is the deuterium labeled Mefuparib (HY-167927). Mefuparib (CVL218) is a poly ADP-ribose polymerase (PARP) inhibitor used in cancer research that exhibits potent brain penetration due to its high protein binding.
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Cat. No.: HY-N1439
CAS No.: 96553-02-5
Synonyms: Gypsogenin-3-O-(6-O-methyl)-glucoside
Methyl gypsogenin-3-O-glucuronide (Gypsogenin-3-O-(6-O-methyl)-glucoside) is a ubiquitous saponin precursor in plants of the genus Gypsophila .
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Cat. No.: HY-N12299
CAS No.: 166196-16-3
Synonyms: Quercetin 3-O-β-D-glucuronide butyl ester
Parthenosin (Quercetin 3-O-β-D-glucuronide butyl ester) is a flavonoid, that can be isolated from the aerial parts of Calligoum polygonoides. Parthenosin shows cytotoxic activity against HepG2 and MCF-7 cell lines with IC50 values of 60.46 and 61.4 μg/mL, respectively .
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Cat. No.: HY-W740051
CAS No.: 78147-42-9
13-cis Retinoyl β-D-glucuronide is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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Cat. No.: HY-W780205
CAS No.: 1237479-05-8
(Rac)-Hesperetin 3'-O-β-D-glucuronide is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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Cat. No.: HY-176333
Target:  

Adrenergic Receptor

Nebivolol O-β-D-glucuronide is a derivative of Nebivolol (HY-B0203). Nebivolol is an orally active beta receptor blocker and has the high beta(1)-receptor affinity. Nebivolol has direct vasodilator properties and adrenergic blocking characteristics. Nebivolol can be used for the research of kinds of diseases such as hypertension, coronary artery disease, congestive heart failure and ischemic heart disease .
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Cat. No.: HY-125156
CAS No.: 1351438-75-9
Purity:  ≥99.0%
Synonyms: BMS-801576
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Dapagliflozin-3-O-β-D-glucuronide (BMS-801576) is the metabolite of Dapagliflozin (HY-10450), and is formed in the liver and kidney by uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9). Dapagliflozin is a selective inhibitor for SGLT2, that can be used to improve glycemic control and attenuate type 2 diabetes .
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Cat. No.: HY-W700218
CAS No.: 115005-78-2
4-Hydroxy propofol 4-O-β-D-Glucuronide is a class of biochemical reagents used in the study of glycobiology. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .
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Cat. No.: HY-W791535
CAS No.: 114991-25-2
4-Hydroxy propofol 1-O-β-D-glucuronide is a class of biochemical reagents used in the study of glycobiology. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .
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Cat. No.: HY-167926S
Mycophenolic Acid-d3 beta-D-Glucuronide is the deuterium labeled 3-Bromo-4,5-dihydroxybenzoic acid methyl ester (HY-167926). 3-Bromo-4,5-dihydroxybenzoic acid methyl ester is a marine-derived natural product known for its biological activity, specifically showcasing antioxidant properties and potential therapeutic applications against oxidative stress-related diseases.
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Cat. No.: HY-126194
CAS No.: 204853-33-8
Synonyms: Ro 61-1448
Tolcapone 3-β-D-glucuronide (Ro 61-1448) is an O-methyl metabolite of Tolcapone (HY-17406) and is pharmacologically inactive. Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC50of 773 nM. Tolcapone can inhibits α-syn and Aβ42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma .
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Cat. No.: HY-W767542
Dihydro Isoferulic Acid-d3 3-O-b-D-Glucuronide is the deuterium labeled (2S,3S,4S,5R,6S)-6-(5-(2-Carboxyethyl)-2-methoxyphenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid (HY-W703563).
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Cat. No.: HY-W006081
CAS No.: 4920-77-8
Target:  

UGT

Research Areas:  

Others

3-Methyl-2-nitrophenol is a UDP-glucuronyltransferase (EC 2.4.1.17) acceptor substrate that can be confirmed to undergo glucuronidation catalyzed by the enzyme to form a glucuronide conjugate. 3-Methyl-2-nitrophenol functions as a substrate for conjugation, with glucuronidation forming a glucuronide conjugate that eliminates the parent compound’s characteristic yellow color. 3-Methyl-2-nitrophenol has higher lipid solubility that contributes to high glucuronidation conversion rate, and exhibits lower absorbance at 340 nm to act as a less interfering substrate for the NADH-NAD +-linked UDP-glucuronyltransferase assay .
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Cat. No.: HY-W048545
CAS No.: 73464-50-3
Synonyms: β-D-Glucopyranuronic acid, methyl ester, 2,3,4-triacetate
Target:  

Drug Intermediate

Research Areas:  

Infection

2,3,4-Tri-O-acetyl-β-D-glucuronide methyl ester (β-D-Glucopyranuronic acid, methyl ester, 2,3,4-triacetate) is a synthetic intermediate in the synthesis of prodrug forms of the antitumor antibiotic Daunomycin (HY-13062A).
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Cat. No.: HY-148044
CAS No.: 372495-52-8
Purity:  99.33%
Research Areas:  

Infection

UNC10201652 is a potent Loop 1 (L1)-specific gut bacterial β-glucuronidase (GUSs) inhibitor with an IC50 value of 0.117 μM for E. coli GUS. UNC10201652 can block SN-38 glucuronide (HY-126373) processing only in individuals whose fecal gut microbiota is highly abundant in L1 GUS enzymes .
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Cat. No.: HY-W014277
CAS No.: 24157-81-1
Target:  

Drug Metabolite

Research Areas:  

Others

2,6-Diisopropylnaphthalene is a substituted naphthalene compound, metabolite precursor and potato sprout inhibitor. 2,6-Diisopropylnaphthalene is metabolized in rats only via oxidation of its isopropyl chains, producing five major unconjugated urinary metabolites, glucuronide conjugates of these metabolites, while a small amount of the parent drug is excreted in urine. 2,6-Diisopropylnaphthalene inhibits sprouting of stored potato tubers; when used alone, it only provides a short-term sprout-inhibiting effect .
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Cat. No.: HY-157129
CAS No.: 1943510-86-8
Target:  

AMPK

Research Areas:  

Cardiovascular Disease

AMPK-α1β1γ1 activator 1 (M1) is an acyl glucuronide metabolite of Indole-3-carboxylic Acid-based AMPK activator. AMPK-α1β1γ1 activator 1 can selectively activated human β1 isoforms with an EC50 value of 38.1nM. AMPK-α1β1γ1 activator 1 can direct binding with human AMPK α1β1γ1 isoform. AMPK-α1β1γ1 activator 1 can be used for the research of diabetic nephropathy .
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Cat. No.: HY-E70973
Research Areas:  

Others

β-Glucuronidase/Arylsulfatase, Helix pomatia is an enzyme with arylsulfatase activity that is isolated from Roman snails (Helix pomatia). β-Glucuronidase/Arylsulfatase, Helix pomatia exhibits broad-spectrum hydrolytic specificity towards various β-glucuronides and sulfate conjugates. β-Glucuronidase/Arylsulfatase, Helix pomatia is used for simultaneous deconjugation of drug-conjugated metabolites in urine samples .
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Cat. No.: HY-148379
CAS No.: 17736-20-8
Target:  

Drug Intermediate

Research Areas:  

Others

Tetrahydrocortisone acetate is a intermediate product for production of tetrahydrocortisone 3-glucuronide .
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Cat. No.: HY-N7176R
CAS No.: 22688-78-4
Synonyms: Kaempferol-3-glucuronide (Standard); Kaempferol-3-O-glucuronide (Standard)
Prosulfocarb (Standard) is the analytical standard of Prosulfocarb. This product is intended for research and analytical applications. Prosulfocarb is a herbicide with a rapidly growing use trend. Prosulfocarb is used in winter cereals to help address the problem of increasing biotic resistance of weeds to certain pesticides. Environmental and food effects of prosulfocarb have been observed, and its transfer pattern from target crops to non-target areas has been studied. The volatility effect of prosulfocarb is an important factor explaining the inefficiency of isolated area contamination and marginal protection against residue spread .
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