118 Results for "

AS1-6

" in MedChemExpress (MCE) Product Catalog:
Products (118)

118 Results for "AS1-6" in MCE Product Catalog:

Cat. No.: HY-15407AS1
Purity:  98.78%
Synonyms: AHU-377-d4 hemicalcium salt
Sacubitril-d4 hemicalcium salt is the deuterium labeled Sacubitril hemicalcium salt (HY-15407A). Sacubitril hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM .
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Cat. No.: HY-17042AS1
CAS No.: 2070015-04-0
Cetirizine-d8 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
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Cat. No.: HY-17503AS1
Metoprolol-d6 (succinate) is deuterium labeled Metoprolol (succinate). Metoprolol succinate is an orally active, selective β1-adrenoceptor antagonist. Metoprolol succinate shows anti-inflammation, antitumor and anti-angiogenic properties .
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Cat. No.: HY-12784AS1
CAS No.: 2712364-69-5
Synonyms: Chlorguanide triazine-d6 hydrochloride
Cycloguanil-d6 (Chlorguanide triazine-d6) hydrochloride is the deuterium labeled Cycloguanil hydrochloride (HY-12784A). Cycloguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 10.8 μM against human DHFR. Cycloguanil hydrochloride blocks the folate metabolic pathway, thereby affecting nucleotide synthesis and interfering with DNA replication. Cycloguanil hydrochloride inhibits DHFR in Plasmodium and is thus used in malaria research. Cycloguanil hydrochloride also potently inhibits DHFR in human cancer cells and blocks the transcriptional activity of STAT3, thereby exhibiting anticancer activity .
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Cat. No.: HY-10163AS1
Dabigatran-d5 (hydrochloride) is the deuterium labeled Dabigatran hydrochloride .
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Cat. No.: HY-10353AS1
Synonyms: MK-0518-13C,d3 potASsium
Raltegravir- 13C,d3 potassium is 13C labeled Raltegravir potassium (HY-10353A). Raltegravir (MK 0518) potassium is a potent integrase (IN) inhibitor, used to treat HIV infection.
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Cat. No.: HY-103641AS1
CAS No.: 2748638-78-8
Synonyms: (2R)-Octyl-2-HG-d17
(2R)-Octyl-α-hydroxyglutarate-d17 ((2R)-Octyl-2-HG-d17) is deuterium labeled (2R)-Octyl-α-hydroxyglutarate (HY-103641). (2R)-Octyl-α-hydroxyglutarate is a modified form of S-isomer 2-Hydroxyglutarate .
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Cat. No.: HY-10581AS1
CAS No.: 1189946-71-1
Synonyms: AM-1155-d4 hydrochloride; BMS-206584-d4 hydrochloride; PD135432-d4 hydrochloride
Gatifloxacin-d4 (AM-1155-d4; BMS-206584-d4; PD135432-d4) hydrochloride is deuterium-labeled Gatifloxacin (hydrochloride) (HY-10581A) .
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Cat. No.: HY-109101AS1
Risdiplam-hydroxylate-d3 is a Risdiplam-hydroxylate tritium substitute. Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels .
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Cat. No.: HY-113056AS1
N1-Acetylspermidine-d3 hydrochloride is the deuterium labeled N1-Acetylspermidine hydrochloride (HY-113056A). N1-Acetylspermidine hydrochloride is an acetyl derivative of polyamines and a substrate for polyamine oxidase (PAO). N1-Acetylspermidine hydrochloride can promote Apoptosis in combination with Procyanidins. N1-Acetylspermidine hydrochloride has a certain cleavage efficiency at apurinic sites of DNA. N1-Acetylspermidine hydrochloride can be used in colorectal cancer research .
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Cat. No.: HY-113208AS1
Synonyms: 11β-13,14-Dihydro-15-keto PGF2α-d4; 11-epi-13,14-Dihydro-15-keto PGF2α-d4
11β-13,14-Dihydro-15-keto Prostaglandin F2α-d4 is is the deuterium labeled 11β-13,14-dihydro-15-keto Prostaglandin F2α.
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Cat. No.: HY-113359AS1
Synonyms: UDP-13C9 dilithium
Uridine 5'-diphosphate- 13C9 (UDP-13C9 ) dilithium is 13C-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y6 receptor agonist with an EC50 of 0.013 μM for human P2Y6 receptor .
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Cat. No.: HY-113468AS1
Synonyms: 3-Methoxy-L-tyrosine-d3 hydrate; 3-O-Methyl-L-DOPA-d3 hydrate
3-O-Methyldopa-d3 (hydrate) is the deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa (3-Methoxy-L-tyrosine) hydrate is a metabolite of L-DOPA (HY-N0304) that can cross the blood-brain barrier (BBB). 3-O-Methyldopa hydrate inhibits the astrocyte-mediated protective effect of L-DOPA (HY-N0304) on dopaminergic neurons. In addition, 3-O-Methyldopa hydrate has certain antidepressant and neuroprotective activities. 3-O-Methyldopa hydrate can be used in the research of nervous system diseases such as depression and Parkinson's disease .
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Cat. No.: HY-117743AS1
Synonyms: SKF-108566J free bASe-d6 hydrochloride
Eprosartan-d6 hydrochloride is deuterated labeled Eprosartan.
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Cat. No.: HY-119695AS1
Synonyms: TenivAStatin-d9 ammonium
Simvastatin acid-d9 ammonium is deuterated labeled Simvastatin acid ammonium (HY-119695A). Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
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Cat. No.: HY-126857AS1
Synonyms: Hydroxyomeprazole-13C,d2 sodium
5-Hydroxyomeprazole- 13C,d2 sodium is 13C and deuterated labeled 5-Hydroxyomeprazole sodium (HY-126857A).
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Cat. No.: HY-13256AS1
CAS No.: 2012598-45-5
Synonyms: OSI-420-d4-1 free bASe; CP-373420-d4-1
Desmethyl Erlotinib-d4-1 (OSI-420-d4-1 (free base); CP-373420-d4-1) is deuterium-labeled Desmethyl Erlotinib (HY-13256A) .
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Cat. No.: HY-133171AS1
CAS No.: 1346617-46-6
(R)-Norfluoxetine-d5 Phthalimide (Phenyl-d5) is the deuterium labeled (R)-Norfluoxetine Phthalimide (Phenyl) .
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Cat. No.: HY-13502AS1
Synonyms: Mitozantrone-d8 hydrochloride; NSC 301739-d8 hydrochloride
Mitoxantrone-d8 (hydrochloride) (Mitozantrone-d8 (hydrochloride)) is deuterium labeled Mitoxantrone (dihydrochloride). Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity . Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively .
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Cat. No.: HY-135336AS1
CAS No.: 1329611-24-6
Synonyms: (S)-(-)-Verapamil-d6 (hydrochloride)
(S)-Verapamil-d6 ((S)-(-)-Verapamil-d6) hydrochloride is the deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells .
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