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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
87 Results for "
Curcumin II-d7
" in MedChemExpress (MCE) Product Catalog:
Products (87)
87 Results for "Curcumin II-d7" in MCE Product Catalog:
Synonyms: CUR5-8
Research Areas:
Curcumin 5-8 (CUR5-8) is a potent and orally active naturally active curcumin (CUR) analog. Curcumin 5-8 inhibits lipid droplet formation. Curcumin 5-8 increases autophagy and inhibits Apoptosis. Curcumin 5-8 improves insulin resistance and insulin sensitivity .
Cat. No.: HY-N0005S
CAS No.: 1246833-26-0
Synonyms: Diferuloylmethane-d6; Natural Yellow 3-d6; Turmeric yellow-d6
Cat. No.: HY-N2521
CAS No.: 52328-97-9
Synonyms: FLLL31
Cat. No.: HY-W002879
CAS No.: 269409-70-3
Synonyms: DiMC; CHC 004; Di-O-methylCurcumin
Target:
Research Areas:
Dimethoxycurcumin is a derivative of curcumin that has anti-inflammatory and antioxidant activities .
Target:
Research Areas:
TML-6, an orally active curcumin derivative, inhibits the synthesis of the β-amyloid precursor protein and β-amyloid (Aβ). TML-6 can upregulate Apo E, suppress NF-κB and mTOR, and increase the activity of the anti-oxidative Nrf2 gene. TML-6 has the potential for Alzheimer’s disease (AD) research .
Synonyms: PGV-1
Pentagamavunon-1 (PGV-1), a Curcumin analog with oral activity, targets on several molecular mechanisms to induce apoptosis including inhibition of angiogenic factors cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF). PGV-1 inhibits NF-κB activation .
Cat. No.: HY-P5485
CAS No.: 271798-75-5
Cat. No.: HY-W110707
CAS No.: 143-27-1
Synonyms: Hexadecylamine
Target:
Research Areas:
Cetylamine (Hexadecylamine) is an amphipathic hexadecyl alkylamine. Cetylamine enhances phase separation of aqueous PVA solutions, promotes the formation of PVA crystalline domains while remaining amorphous itself, and enables the preparation of surfactant-free, solvent-free, and crosslinker-free PVA hydrogels via freeze-thaw blending. Cetylamine can serve as the cationic surfactant component in ion-crosslinked micelles, which can load hydrophobic drugs and deliver them to breast cancer cells. Cetylamine is applicable to breast cancer-related research .
Cat. No.: HY-N0007AR
CAS No.: 24939-16-0
Synonyms: Curcumin III (Standard); DidemethoxyCurcumin (Standard)
Cat. No.: HY-N0006R
CAS No.: 22608-11-3
Synonyms: Curcumin II (Standard); DesmethoxyCurcumin (Standard); MonodemethoxyCurcumin (Standard)
Cat. No.: HY-N0006S1
Synonyms: Curcumin II-d4; DesmethoxyCurcumin-d4; MonodemethoxyCurcumin-d4
Cat. No.: HY-N0893R
CAS No.: 36062-04-1
Synonyms: HZIV 81-2 (Standard)
Cat. No.: HY-W509797
CAS No.: 21618-92-8
Target:
Drug Metabolite TNF Receptor IKK NF-κB Autophagy NOD-like Receptor (NLR) NADPH Oxidase Keap1-Nrf2
Research Areas:
5-(3',4'-Dihydroxyphenyl)-γ-valerolactone is an intestinal microbiota metabolite of (-)-Epicatechin (HY-N0001). 5-(3',4'-Dihydroxyphenyl)-γ-valerolactone downregulates TNF-α-stimulated phosphorylation of IKK and IκBα, inhibits the transcriptional activation of NF-κB, and suppresses the expression of adhesion molecules and chemokines. 5-(3',4'-Dihydroxyphenyl)-γ-valerolactone promotes autophagy, alleviates oxidative stress, maintains osteoblast differentiation, induces G1 phase arrest, inhibits adipogenesis, and scavenges ABTS free radicals. 5-(3',4'-Dihydroxyphenyl)-γ-valerolactone inhibits the adhesion of uropathogenic Escherichia coli to bladder epithelial cells; when used in combination with Curcumin (HY-N0005), it downregulates the NLRP3 and NOX2/Nrf2 signaling pathways, thereby reducing microglial activation. 5-(3',4'-Dihydroxyphenyl)-γ-valerolactone can be used in research related to diabetes, atherosclerosis, osteoporosis, obesity, neurodegenerative diseases involving microglial activation, and urinary tract infections [7] .
Cat. No.: HY-N0007R
CAS No.: 33171-05-0
Synonyms: (E,E)-Curcumin III (Standard); (E,E)-DidemethoxyCurcumin (Standard)
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Cat. No.: HY-179228
CAS No.: 1246964-08-8
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AN02 is a derivative of Curcumin (HY-N0005). AN02 inhibits the proliferation and clonogenicity, migration and invasion of ovarian cancer cells. AN02 dose-dependently upregulates the expression of APC and mediates the degradation of CTLA-4 through SMAD4. In the small xenograft model, AN02 significantly inhibits tumor growth and reverses the tumor immune-suppressive microenvironment. AN02, when combined with Ipilimumab (HY-P9901), can enhance efficacy and inhibit epithelial-mesenchymal transition. AN02 can be used for the study of ovarian cancer .
Cat. No.: HY-N0894R
CAS No.: 36062-07-4
Synonyms: HexahydrobisdemethoxyCurcumin (Standard)
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Target:
Cat. No.: HY-N7275
CAS No.: 824951-60-2
Category:
Natural Products Plants Curcuma longa Disease Research Fields Inflammation/Immunology Zingiberaceae
Target:
UBS109, as a curcumin analogue, can promote the differentiation and mineralization of osteoblasts. UBS109 shows to regulate bone cell function by activating Smad and inhibiting NF-kB. UBS109 can be used in bone tissue engineering and osteoporosis research .
Cat. No.: HY-N0929R
CAS No.: 36062-05-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
