27060-70-4
27060-70-4
Chemical Structure
Pentagamavunon-1
Synonym(s): PGV-1
- CAS No.: 27060-70-4
- Formula:C23H24O3
- Molecular Weight:348.43
IUPAC Name: 2,5-bis((E)-4-hydroxy-3,5-dimethylbenzylidene)cyclopentan-1-one
InChIKey: OHSKJRMWVIVJCP-AYKLPDECSA-N
SMILES: O=C1/C(CC/C1=C\C2=CC(C)=C(O)C(C)=C2)=C/C3=CC(C)=C(O)C(C)=C3
Biological Activity: Pentagamavunon-1 (PGV-1), a Curcumin analog with oral activity, targets on several molecular mechanisms to induce apoptosis including inhibition of angiogenic factors cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF). PGV-1 inhibits NF-κB activation[1].
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Pentagamavunon-1 | 98.95% | Pentagamavunon-1 (PGV-1), a Curcumin analog with oral activity, targets on several molecular mechanisms to induce apoptosis including inhibition of angiogenic factors cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF). PGV-1 inhibits NF-κB activation. | ||||||||||||||||||||
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