24939-16-0
Chemical Structure
Bisdemethoxycucurmin
Synonym(s): Curcumin III; Didemethoxycurcumin
- CAS No.: 24939-16-0
- Formula:C19H16O4
- Molecular Weight:308.33
IUPAC Name: (1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
InChIKey: PREBVFJICNPEKM-YDWXAUTNSA-N
SMILES: O=C(CC(/C=C/C1=CC=C(O)C=C1)=O)/C=C/C2=CC=C(O)C=C2
Biological Activity: Bisdemethoxycucurmin (Curcumin III) is a curcuminoid compound and an inhibitor of P-glycoprotein and ferroptosis. Bisdemethoxycucurmin exhibits multiple activities such as anti-oxidation, anti-inflammation and anti-tumor. Bisdemethoxycucurmin can be used for the research of tumors and inflammatory diseases[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bisdemethoxycucurmin | 98.77% | Bisdemethoxycucurmin (Curcumin III) is a curcuminoid compound and an inhibitor of P-glycoprotein and ferroptosis. Bisdemethoxycucurmin exhibits multiple activities such as anti-oxidation, anti-inflammation and anti-tumor. Bisdemethoxycucurmin can be used for the research of tumors and inflammatory diseases. | ||||||||||||||||||||
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Bisdemethoxycucurmin (Standard) | 98.33% | Bisdemethoxycucurmin (Standard) (Curcumin III (Standard)) is the analytical standard of Bisdemethoxycucurmin (HY-N0007A). This product is intended for research and analytical applications. Bisdemethoxycucurmin (Curcumin III) is a curcuminoid compound and an inhibitor of P-glycoprotein and ferroptosis. Bisdemethoxycucurmin exhibits multiple activities such as anti-oxidation, anti-inflammation and anti-tumor. Bisdemethoxycucurmin can be used for the research of tumors and inflammatory diseases. | ||||||||||||||||||||
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Similarity Score 1.00
HY-N0007(E,E)-Bisdemethoxycurcumin -
Similarity Score 0.82
HY-N119021,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one -
Similarity Score 0.79
HY-N0006A(E/Z)-Demethoxycurcumin -
Similarity Score 0.79
HY-N0006RDemethoxycurcumin (Standard) -
Similarity Score 0.78
HY-N09951,7-Bis(4-hydroxyphenyl)hept-1-en-3-one -
Similarity Score 0.76
HY-N98761,7-Bis(4-hydroxyphenyl)-5-hydroxyhept-1-en-3-one -
Similarity Score 0.76
HY-N09981,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one -
Similarity Score 0.75
HY-N101581,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one -
Similarity Score 0.75
HY-N2230A(E/Z)-N-p-trans-Coumaroyltyramine -
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References
- [1]. Zhang P, et al. Cynarin alleviates intervertebral disc degeneration via protecting nucleus pulposus cells from ferroptosis. Biomed Pharmacother. 2023 Sep;165:115252. [Content Brief]
- [2]. Nagabhushan, et al. Curcumin as an inhibitor of cancer. Journal of the American College of Nutrition 11.2. 1992. 192-198.
- [3]. Chearwae W, et al. Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder. Biochem Pharmacol. 2004 Nov 15;68(10):2043-52. [Content Brief]
