271798-75-5
Chemical Structure
Dabcyl-QALPETGEE-Edans
- CAS No.: 271798-75-5
- Formula:C67H89N15O21S
- Molecular Weight:1472.58
InChIKey: YYEHPZAOYVLULL-YSAYQOMWSA-N
SMILES: O=C(C1=CC=C(/N=N/C2=CC=C(N(C)C)C=C2)C=C1)N[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCCNC4=CC=CC5=C4C=CC=C5S(=O)(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CCC3)=O)CC(C)C)=O)C)=O)CCC(N)=O
Biological Activity: Dabcyl-QALPETGEE-Edans is a synthetic peptide substrate for fluorescence resonance energy transfer (FRET) detection of Sortase A (SrtA) enzymatic activity. Dabcyl-QALPETGEE-Edans is labeled at both ends with the fluorescent group Edans (donor) and the quencher Dabcyl (acceptor), respectively. Dabcyl-QALPETGEE-Edans's central sequence contains a conserved motif specifically recognized by SrtA. Dabcyl-QALPETGEE-Edans demonstrates high sensitivity in vitro assays, enabling precise determination of the half-maximal inhibitory concentration of SrtA[1].
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Dabcyl-QALPETGEE-Edans | 98.04% | Dabcyl-QALPETGEE-Edans is a synthetic peptide substrate for fluorescence resonance energy transfer (FRET) detection of Sortase A (SrtA) enzymatic activity. Dabcyl-QALPETGEE-Edans is labeled at both ends with the fluorescent group Edans (donor) and the quencher Dabcyl (acceptor), respectively. Dabcyl-QALPETGEE-Edans's central sequence contains a conserved motif specifically recognized by SrtA. Dabcyl-QALPETGEE-Edans demonstrates high sensitivity in vitro assays, enabling precise determination of the half-maximal inhibitory concentration of SrtA. | ||||||||||||||||||||
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Keywords
