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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
DHX9
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "DHX9" in MCE Product Catalog:
Cat. No.: HY-157609
CAS No.: 2973747-13-4
Target:
Research Areas:
DHX9-IN-12 (83) is a RNA helicase DHX9 inhibitor, with an EC50 of 0.917 μM in DHX9 cellular target engagement. Used in cancer research .
Cat. No.: HY-157610
CAS No.: 2973747-90-7
Target:
Research Areas:
DHX9-IN-14 (161) is a RNA helicase DHX9 inhibitor, with an EC50 of 3.4 μM in DHX9 cellular target engagement. Used in cancer research .
Cat. No.: HY-179322
CAS No.: 2973401-72-6
Target:
Research Areas:
DHX9-IN-21 is a DHX9 inhibitor with an IC50 of 12.2 nM; its EC50 at the cellular level is 0.3 μM. DHX9-IN-21 can be used for the research of microsatellite unstable colorectal cancer .
Cat. No.: HY-185723
Target:
Research Areas:
rG4 WT_AHPC_PEG2 is a selective RNA G-quadruplex-based DHX36 PROTAC degrader with a Kd value of 79.7 nM. rG4 WT_AHPC_PEG2 degrades DHX36 via a proteasome-dependent mechanism, without significantly degrading other G4-binding proteins including NCL, DHX9, hnRNP, SRSF and FMR1 .
Cat. No.: HY-P703111
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: DHX9; ATP-Dependent RNA Helicase A; Prev. DDX9; NDH II; Prev. LKP; NDH2; Nuclear DNA Helicase II; DEAH (Asp-Glu-Ala-His) Box Polypeptide 9; RNA Helicase A; DEAH-Box Helicase 9; Leukophysin; RNA Helicase; RHA; MRD75; DEAD/H (Asp-Glu-Ala-Asp/His) Box Polype
Species:
Human
Source:
E. coli
Cat. No.: HY-P705681
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: DHX9; ATP-Dependent RNA Helicase A; Prev. DDX9; NDH II; Prev. LKP; NDH2; Nuclear DNA Helicase II; DEAH (Asp-Glu-Ala-His) Box Polypeptide 9; RNA Helicase A; DEAH-Box Helicase 9; Leukophysin; RNA Helicase; RHA; MRD75; DEAD/H (Asp-Glu-Ala-Asp/His) Box Polype
Species:
Human
Source:
E. coli
Cat. No.: HY-181440
CAS No.: 3092641-80-7
Target:
Research Areas:
TDG-IN-1 is an orally active, selective small-molecule inhibitor of thymine DNA glycosylase (TDG) with a Ka of 1.46 nM. TDG-IN-1 impairs the DNA-binding ability of TDG, induces downregulated expression of DHX9, accumulation of double-stranded RNA, and activation of the RIG-I/MDA5-MAVS pathway, while acting as a tumor suppressor, innate immune activator and immunostimulant. TDG-IN-1 inhibits the growth of p53-deficient tumor cells and xenograft tumors, and exerts a synthetic lethal effect with p53. TDG-IN-1 is applicable to the research of p53-deficient cancers .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
