167 Results for "

Fibronectin

" in MedChemExpress (MCE) Product Catalog:
Products (167)

167 Results for "Fibronectin" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P80493
Synonyms: Fibronectin, FN, Fn1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IF-Tissue

Reactivity:  

Human, Mouse

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1
1 Cited Publications
Cat. No.: HY-P80674
Synonyms: FN1; FN; Fibronectin; FN; Cold-insoluble globulin; CIG

Host:  

Mouse

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P70201
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FLRT2; Leucine-Rich Repeat Transmembrane Protein FLRT2; Fibronectin Leucine Rich Transmembrane Protein 2; KIAA0405; Fibronectin-Like Domain-Containing Leucine-Rich Transmembrane Protein 2
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P77718
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: ITGA5; Integrin Alpha-F; Prev. FNRA; CDNA FLJ50382, Moderately Similar To Integrin Alpha-5; CD49e; Very Late Activation Protein 5, Alpha Subunit; Integrin, Alpha 5 (Fibronectin Receptor, Alpha Polypeptide); Fibronectin Receptor, Alpha Subunit; Fibronectin
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P86388
Synonyms: ITGB1; FNRB; MDF2; MSK12; Integrin beta-1; Fibronectin receptor subunit beta; VLA-4 subunit beta; CD antigen CD29

Host:  

Rabbit

Application:  

WB, IHC-P, ELISA, IF-Tissue

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-E70005C
CAS No.: 9001-12-1
Target:  

MMP

Research Areas:  

Others

Collagenase, Type III is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type III breaksdown collagens1, 4, 9, 10, 14, fibronectin, MMP-9, gelatin, plasminogen, aggrecan,perlecan osteonectin

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Cat. No.: HY-P3160C
CAS No.: 86088-83-7
Fibronectin, bovine plasma is a fibronectin derived from bovine plasma. Fibronectin is an extracellular matrix protein that is upregulated and essential in many developmental processes, and also exists in the pathological progression of tissues and wound healing. Fibronectin specifically binds to a large number of molecules, including other components of the extracellular matrix, signaling molecules and cell adhesion molecules. The interaction between cells and fibronectin leads to bidirectional crosstalk, which regulates cell functions and induces cell-dependent changes in the extracellular matrix. Fibronectin, bovine plasma inhibits the production of bovine leukemia virus (BLV) p24 core protein in naturally infected bovine peripheral blood mononuclear cells .
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Cat. No.: HY-P10709
CAS No.: 847058-45-1
Target:  

Collagen

Research Areas:  

Cardiovascular Disease Cancer

CREKA peptide is a selective non-covalent binding agent targeting fibrin, type IV collagen, and fibronectin, often used as a targeting ligand to modify delivery carriers. CREKA peptide specifically recognizes fibrin, fibronectin, and type IV collagen that are excessively deposited in the tumor microenvironment or fibrotic tissue, mediating the targeted accumulation of the carrier at the lesion site and promoting drug internalization into target cells (such as cancer cells and activated hepatic stellate cells). CREKA peptide can enhance targeted delivery efficiency, increase drug concentration at the lesion site, and reduce systemic side effects .
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Cat. No.: HY-P3522
CAS No.: 107978-83-6
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

REDV is the minimal active sequence within the CS5 site of the alternatively spliced type III connecting segment (IIICS) region of fibronectin. REDV can mediate adhesion to the IIICS region of plasma fibronectin by binding the integrin alpha 4 beta 1(α4β1). REDV can be used for the research of cell adhesion. REDV is used to study the effects of gene vectors containing REDV on cells .
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Cat. No.: HY-P0322
CAS No.: 111119-28-9
Synonyms: EMD 56574
Target:  

Integrin

GRGDSPK (EMD 56574) is a peptide incluing Arg-Gly-Asp (RGD). GRGDSPK (EMD 56574) is an competitive and reversible inhibitory peptide for inhibiting integrin-fibronectin binding. GRGDSPK is used to study the role of integrins in bone formation and resorption .
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Cat. No.: HY-NP175
CAS No.: 9064-67-9
Collagen (bovine skin) is a three-dimensional cell culture matrix and morphoregulator extracted from bovine skin, which binds to integrins (such as α1β1, α2β1, α11β1) and discoidin domain receptors (DDR1 and DDR2). Collagen (bovine skin) can be reconstituted into a three-dimensional fibrous network to mimic the in vivo tissue environment. It can not only be modified through cross-linking or concentration adjustment, but also interact with fibronectin to enhance matrix-associated cellular activities. Collagen (bovine skin) mediates the proliferation, aggregation, durotactic migration and differentiation of fibroblasts, regulates the synthesis, remodeling and contraction of extracellular matrix, and modulates the expression, activation of MMP as well as cell apoptosis, etc. Collagen (bovine skin) can be used in studies related to the mechanisms of cancer occurrence and development .
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Cat. No.: HY-P99479
CAS No.: 1957239-90-5
Synonyms: L19-IL2

Target:  

Interleukin Related

Research Areas:  

Cancer

Bifikafusp alfa (L19-IL2) is an immunoresearch fusion protein consisting of human L19 antibodies fused to the human cytokine interleukin 2 (IL2).Bifikafusp alfa is specific to the EDB domain of fibronectin. Bifikafusp alfa has anticancer activity .
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Cat. No.: HY-P0104
CAS No.: 1447824-23-8
Target:  

Collagen

Research Areas:  

Metabolic Disease

Palmitoyl tripeptide-38 is a lipopeptide that increases the production of dermal and epidermal collagen, fibronectin, and hyaluronic acid. Palmitoyl tripeptide-38 is used in research related to skin aging (fine lines, wrinkles, reduced skin elasticity, decreased skin water content, uneven skin tone) .
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Cat. No.: HY-107639
CAS No.: 230961-21-4
Purity:  96.70%
Target:  

MMP

Research Areas:  

Inflammation/Immunology

UK-370106 is a potent and highly selective MMP-3 (IC50 of 23 nM) and MMP-12 (IC50 of 42 nM) inhibitor with >1200-fold higher potency than MMP-1, MMP-2, MMP-9, and MMP-14, and about 100-fold than MMP-13 and MMP-8. UK-370106 potently inhibits cleavage of [ 3H]-fibronectin by MMP-3 (IC50 of 320 nM) and has little effect on keratinocyte migration in vitro .
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Cat. No.: HY-112247
CAS No.: 2088135-12-8
Purity:  99.89%
SR 16832 is a dual-site covalent, orthosteric and allosteric PPARγ antagonist. SR 16832 activates the TGF-β signaling pathway and upregulates the expression of Vimentin and Fibronectin (Fibronectin). SR 16832 is toxic to bronchial epithelium. SR 16832 can be used in research related to type 2 diabetes and pulmonary fibrosis .
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Cat. No.: HY-P0306
CAS No.: 125720-21-0
Synonyms: Heparin Binding Peptide
Target:  

Others

Research Areas:  

Cardiovascular Disease

Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (MSC) spheroids into larger aggregates. Fibronectin Adhesion-promoting Peptide directly promotes the adhesion, spreading, and migration of endothelial cells by reacting with heparin binding domains of cells .
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Cat. No.: HY-P2532
CAS No.: 278792-07-7
Target:  

Integrin

Research Areas:  

Others

Integrin Binding Peptide is derived by fibronectin. Integrin Binding Peptide can be used for PEG hydrogel preparation .
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Cat. No.: HY-12093A
CAS No.: 1258003-93-8
Target:  

Drug Isomer MMP Cadherin

Research Areas:  

Inflammation/Immunology

(R)-MMP408 is an isomer of MMP408 (HY-12093). MMP408 is an orally active MMP-12 inhibitor (IC50=2.0 nM for hMMP-12) that effectively interferes with the epithelial-mesenchymal transition (EMT) process. MMP408 significantly upregulates the expression of E-cadherin in nasal epithelial cells, while inhibiting mesenchymal markers such as vimentin, α-smooth muscle actin and fibronectin, thereby reversing the EMT phenotype. MMP408 is used in studies of airway remodeling-related diseases, including chronic rhinosinusitis with nasal polyps, chronic obstructive pulmonary disease (COPD) and asthma .
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Cat. No.: HY-P1921
CAS No.: 134282-68-1
Target:  

Integrin Thrombin

Research Areas:  

Cardiovascular Disease

YRGDS Fibronectin Fragment is a fibronectin fragment, an adhesion peptide that displays strong binding affinity to thrombin-stimulated platelets .
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Cat. No.: HY-P10261
CAS No.: 94040-53-6
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Collagen binding peptide is a conserved fibronectin peptide .
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