111119-28-9
111119-28-9
Chemical Structure
GRGDSPK
Synonym(s): EMD 56574
- CAS No.: 111119-28-9
- Formula:C28H49N11O11
- Molecular Weight:715.76
IUPAC Name: glycyl-L-arginylglycyl-L-aspartyl-L-seryl-L-prolyl-L-lysine
InChIKey: ZRVZOBGMZWVJOS-VMXHOPILSA-N
SMILES: O=C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)CN
Biological Activity: GRGDSPK (EMD 56574) is a peptide incluing Arg-Gly-Asp (RGD). GRGDSPK (EMD 56574) is an competitive and reversible inhibitory peptide for inhibiting integrin-fibronectin binding. GRGDSPK is used to study the role of integrins in bone formation and resorption[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GRGDSPK | 98.55% | GRGDSPK (EMD 56574) is a peptide incluing Arg-Gly-Asp (RGD). GRGDSPK (EMD 56574) is an competitive and reversible inhibitory peptide for inhibiting integrin-fibronectin binding. GRGDSPK is used to study the role of integrins in bone formation and resorption. | ||||||||||||||||||||
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References
- [1]. G A Gronowicz, et al. Synthetic Peptide Containing Arg-Gly-Asp Inhibits Bone Formation and Resorption in a Mineralizing Organ Culture System of Fetal Rat Parietal Bones. J Bone Miner Res. 1994 Feb;9(2):193-201. [Content Brief]
- [2]. Pierre-Henri Puech, et al. Measuring Cell Adhesion Forces of Primary Gastrulating Cells From Zebrafish Using Atomic Force Microscopy. J Cell Sci. 2005 Sep 15;118(Pt 18):4199-206. [Content Brief]
