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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
Flt4
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "Flt4" in MCE Product Catalog:
Cat. No.: HY-110272
CAS No.: 212142-18-2
Synonyms: PTK787 succinate; ZK-222584 succinate; CGP-79787 succinate
Vatalanib (PTK787) succinate is a potent and orally active VEGFR inhibitor with IC50s of 37 nM, 77 nM, 270 nM, 660 nM, 730 nM, 1400 nM, and 580 nM for KDR, Flt-1, Flk, Flt-4, c-Kit, c-Fms, and PDGFR-β, respectively .
Cat. No.: HY-13049R
CAS No.: 857036-77-2
Synonyms: AZD-2171 maleate (Standard)
Target:
Research Areas:
Cediranib (maleate) (Standard) is the analytical standard of Cediranib (maleate). This product is intended for research and analytical applications. Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.
Cat. No.: HY-10205R
CAS No.: 288383-20-0
Synonyms: AZD2171 (Standard)
Target:
Research Areas:
Cediranib (Standard) is the analytical standard of Cediranib. This product is intended for research and analytical applications. Cediranib (AZD2171) is a highly potent, orally available VEGFR tyrosine kinase inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.
Cat. No.: HY-10260R
CAS No.: 443913-73-3
Synonyms: ZD6474 (Standard)
Target:
Research Areas:
Vandetanib (Standard) is the analytical standard of Vandetanib. This product is intended for research and analytical applications. Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM) .
Cat. No.: HY-168115
CAS No.: 2648279-77-8
Multi-kinase inhibitor 4 (compound 14) is an orally active inhibitor of FLT1, KDR, FLT3, FLT4, PDGFRα, PDGFRβ, with IC50s of 1.97 nM, 1.04 nM, 0.33 nM, 1.44 nM, 0.18 nM, 0.89 nM. Multi-kinase inhibitor 4 plays an important role in cancer research .
Cat. No.: HY-168114
CAS No.: 2648279-76-7
Multi-kinase inhibitor 3 (compound 12) is a potent and orally active multikinase inhibitor with IC50 values of 1.59, 1.23, 1.19, 0.59, 0.22, 1.15 nM for FLT1/VEGFR1, KDR/VEGFR2, FLT4/VEGFR3, FLT3, PDGFRα, PDGFRβ, respectively. Multi-kinase inhibitor 3 shows antiproliferative activity. Multi-kinase inhibitor 3 shows anticancer activity .
Cat. No.: HY-10260A
CAS No.: 338992-53-3
Synonyms: ZD6474 trifluoroacetate
Vandetanib trifluoroacetate (D6474 trifluoroacetate) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib trifluoroacetate also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM) .
Cat. No.: HY-10260S
CAS No.: 1174683-49-8
Synonyms: ZD6474-d6
Cat. No.: HY-10260S1
CAS No.: 1215100-18-7
Cat. No.: HY-10260S2
CAS No.: 1261397-03-8
Synonyms: ZD6474-13C6
Cat. No.: HY-P78872
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Flt4; Fms Related Tyrosine Kinase 4; Fms Related Receptor Tyrosine Kinase 4; VEGF Receptor-3; VEGFR3; Flt-4; Vascular Endothelial Growth Factor Receptor 3; Vascular Endothelial Growth Factor Receptor 3 Variant; VEGFR-3; Alternative Protein Flt4; Tyrosine-
Species:
Human
Source:
HEK293
Cat. No.: HY-P704278
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Flt4; Fms Related Tyrosine Kinase 4; Fms Related Receptor Tyrosine Kinase 4; VEGF Receptor-3; VEGFR3; Flt-4; Vascular Endothelial Growth Factor Receptor 3; Vascular Endothelial Growth Factor Receptor 3 Variant; VEGFR-3; Alternative Protein Flt4; Tyrosine-
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P74466
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Flt4; Fms Related Tyrosine Kinase 4; Fms Related Receptor Tyrosine Kinase 4; VEGF Receptor-3; VEGFR3; Flt-4; Vascular Endothelial Growth Factor Receptor 3; Vascular Endothelial Growth Factor Receptor 3 Variant; VEGFR-3; Alternative Protein Flt4; Tyrosine-
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P74468
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Flt4; Fms Related Tyrosine Kinase 4; Fms Related Receptor Tyrosine Kinase 4; VEGF Receptor-3; VEGFR3; Flt-4; Vascular Endothelial Growth Factor Receptor 3; Vascular Endothelial Growth Factor Receptor 3 Variant; VEGFR-3; Alternative Protein Flt4; Tyrosine-
Species:
Human
Source:
HEK293
Cat. No.: HY-P74469
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Flt4; Fms Related Tyrosine Kinase 4; Fms Related Receptor Tyrosine Kinase 4; VEGF Receptor-3; VEGFR3; Flt-4; Vascular Endothelial Growth Factor Receptor 3; Vascular Endothelial Growth Factor Receptor 3 Variant; VEGFR-3; Alternative Protein Flt4; Tyrosine-
Species:
Human
Source:
HEK293
Cat. No.: HY-P74467
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Flt4; Fms Related Tyrosine Kinase 4; Fms Related Receptor Tyrosine Kinase 4; VEGF Receptor-3; VEGFR3; Flt-4; Vascular Endothelial Growth Factor Receptor 3; Vascular Endothelial Growth Factor Receptor 3 Variant; VEGFR-3; Alternative Protein Flt4; Tyrosine-
Species:
Mouse
Source:
HEK293
Cat. No.: HY-155178
CAS No.: 2910858-34-1
Antiproliferative agent-34 (Compound A14) is a multi-target kinase inhibitor, with an IC50 of 177 nM and 1567 nM for EGFR L858R/T790M and EGFR WT. Antiproliferative agent-34 also inhibits JAK2, ROS1, FLT3, FLT4, PDGFRα with IC50 of 30.93, 106.90, 108.00, 226.60, 42.53 nM. Antiproliferative agent-34 inhibits H1975 and HCC827 cells proliferation with IC50 values below 40 nM under normoxic condition, and the anti-proliferation potency achieves 4–6-fold improvement (IC50 values < 10 nM) under hypoxic condition .
Cat. No.: HY-P78538
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Flt4; Fms Related Tyrosine Kinase 4; Fms Related Receptor Tyrosine Kinase 4; VEGF Receptor-3; VEGFR3; Flt-4; Vascular Endothelial Growth Factor Receptor 3; Vascular Endothelial Growth Factor Receptor 3 Variant; VEGFR-3; Alternative Protein Flt4; Tyrosine-
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
