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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
Porcn
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "Porcn" in MCE Product Catalog:
Cat. No.: HY-P11606
Cat. No.: HY-17545R
CAS No.: 1243244-14-5
Synonyms: WNT974 (Standard)
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LGK974 (Standard) is the analytical standard of LGK974 (HY-17545). This product is intended for research and analytical applications. LGK974 (WNT974) is an orally bioavailable and specific Porcupine (PORCN) inhibitor with an IC50 of 0.1 nM .
Cat. No.: HY-107570R
CAS No.: 688353-45-9
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IWP-12 (Standard) is the analytical standard of IWP-12 (HY-107570). This product is intended for research and analytical applications. IWP-12 is a potent inhibitor of porcupine (PORCN) and inhibits cell-autonomous Wnt signaling with an IC50 of 15 nM .
Cat. No.: HY-13912R
CAS No.: 686770-61-6
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IWP-2 (Standard) is the analytical standard of IWP-2 (HY-13912). This product is intended for research and analytical applications. IWP-2 is an inhibitor of Wnt processing and secretion with an IC50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. IWP-2 is also an ATP-competitive CK1δ inhibitor with an IC50 of 40 nM for the gatekeeper mutant M82FCK1δ .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
