Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
149 Results for "
Relative
" in MedChemExpress (MCE) Product Catalog:
Products (149)
149 Results for "Relative" in MCE Product Catalog:
Cat. No.: HY-W034344
CAS No.: 2386-57-4
Cat. No.: HY-N4301
CAS No.: 30485-16-6
Target:
Target:
Research Areas:
GSK9027, as a non-steroidal glucocorticoid receptor (GR) agonist, behaves as a partial agonist on the 2×glucocorticoid response element (GRE) reporter system, and achieves intrinsic activities relative to dexamethasone .
Cat. No.: HY-160440
CAS No.: 2307718-96-1
Target:
Research Areas:
rel-VU6021625 is the relative configuration of VU6021625 (HY-160440A). VU6021625 is a potent and selective mAChR M4 antagonist with IC50 values of 0.44 nM and 57 nM for human M4, rat M4, respectively .
Cat. No.: HY-N7259A
CAS No.: 18309-28-9
Category:
Target:
Cat. No.: HY-W337569
CAS No.: 188416-29-7
Synonyms: (±)-UK-109496
(±)-Voriconazole ((±)-UK-109496) is a relative configuration of Voriconazole (HY-76200). Voriconazole is an antifungal agent .
Target:
Research Areas:
Porfiromycin (N-Methylmitomycin C) is a bioreductive alkylating agent that preferentially kill hypoxic tumor cells relative to other aerobic counterparts .
Target:
Cat. No.: HY-16023B
CAS No.: 151533-34-5
Synonyms: EM-343; (Rac)-EM-652
Target:
Research Areas:
(Rac)-Acolbifene (EM-343; (Rac)-EM-652) is the racemic form of EM652 (estrogen receptor?antagonist), has anti-estrogenic and estrogenic activities. (Rac)-Acolbifene (EM-343; (Rac)-EM-652) contains a piperidine ring, shows good pharmacological profile,relative binding affinity (RBA)=380 .
Cat. No.: HY-107508
CAS No.: 890764-36-0
Target:
Research Areas:
VU-29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor (EC50=9 nM and Ki=244 nM for rmGluR5). VU-29 is selective for mGluR5 relative to other mGluR subtypes (EC50: rmGluR1/rmGluR2=557 nM/1.5 μM; hmGluR4=154 nM) .
Cat. No.: HY-W099859
CAS No.: 939-27-5
2-Ethylnaphthalene is an alkyl-substituted polyaromatic. 2-Ethylnaphthalene has a negative correlation with Glomus relative abundance in arbuscular mycorrhizal fungi community .
Research Areas:
F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways, with IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALK WT, ROS1 WT, ALK L1196M and ALK G1202R, respectively .
Cat. No.: HY-167902
CAS No.: 159081-22-8
Target:
Research Areas:
YM-31636 free base is an orally active, potent and selective 5-HT3 receptor agonist with a Ki value of 0.2 nM. YM-31636 free base induces contraction of isolated guinea pig distal colon. YM-31636 free base induces tachycardia with the relative intrinsic activity of approximately 0.23 in isolated guinea pig right atrium. YM-31636 free base is promising for research of constipation .
Cat. No.: HY-D1641
CAS No.: 73630-09-8
Cat. No.: HY-146341
CAS No.: 1338575-38-4
Research Areas:
FAAH-IN-5 (Compound 7) is a relative selective, irreversible fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 10.5 nM. FAAH-IN-5 shows low PAMPA (Parallel Artificial Membrane Permeability Assay) permeability .
Target:
Research Areas:
(R)-PF-06256142 is the R enantiomer of PF-06256142 with low active. PF-06256142 is a potent and selective orthosteric D1 receptor agonist that can reduce receptor desensitization relative to dopamine and other catechol-containing agonists .
Cat. No.: HY-123410
CAS No.: 628263-22-9
Target:
Research Areas:
KM-233 is a classical cannabinoid with good blood brain barrier penetration. KM-233 possesses a selective affinity for the CB2 receptors relative to THC. KM-233 is effective at reducing U87 glioma tumor burden, and can be used for glioma research .
Cat. No.: HY-14552A
CAS No.: 204519-66-4
Synonyms: SB 223412 hydrochloride; SB 223412-A
Target:
Research Areas:
Talnetant (SB 223412) hydrochloride is a selective, competitive, brain-permeable NK3 receptor antagonist with a Ki of 1.4 nM in hNK-3-CHO cells. Talnetant hydrochloride is 100-fold more selective for hNK-3 relative to the hNK-2 receptor and has no affinity for hNK-1. Talnetant hydrochloride can be used in schizophrenia-related studies .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
