Porfiromycin
Based on 1 Customer Validation
Porfiromycin (N-Methylmitomycin C) is a bioreductive alkylating agent that preferentially kill hypoxic tumor cells relative to other aerobic counterparts.
For research use only. We do not sell to patients.
- Purity: 99.52%
- CAS No.: 801-52-5
- Formula: C16H20N4O5
- Molecular Weight:348.35
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF S-180 | ED50 |
22 μg/mL
Compound: 31
|
Antitumor activity against mouse S180 cells implanted in ip dosed ddY mouse assessed as tumor volume after 7 days
Antitumor activity against mouse S180 cells implanted in ip dosed ddY mouse assessed as tumor volume after 7 days
|
[PMID: 19540628] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 801-52-5
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Appearance Solid
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Molecular Weight 348.35
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Formula C16H20N4O5
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Color Brown to black
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SMILES
CO[C@]12N(C[C@@]3([H])[C@]2([H])N3C)C4=C(C(C(N)=C(C4=O)C)=O)[C@H]1COC(N)=O
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Synonyms
N-Methylmitomycin C; NSC-56410; U-14743
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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