GSK9027
Based on 1 Customer Validation
GSK9027, as a non-steroidal glucocorticoid receptor (GR) agonist, behaves as a partial agonist on the 2×glucocorticoid response element (GRE) reporter system, and achieves intrinsic activities relative to dexamethasone.
For research use only. We do not sell to patients.
- Purity: 98.59%
- CAS No.: 1229096-88-1
- Formula: C27H19F4N3O2S
- Molecular Weight:525.52
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
GR[2]
GSK9027 demonstrates reduced 2×GRE reporter activation and is partial agonists[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1229096-88-1
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Appearance Solid
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Molecular Weight 525.52
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Formula C27H19F4N3O2S
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Color White to off-white
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SMILES
O=S(CC1=CC=CC=C1)(NC2=CC=C(C3=CC4=C(N(C5=CC=C(F)C=C5)N=C4)C=C3)C(C(F)(F)F)=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (475.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9029 mL | 9.5144 mL | 19.0288 mL | 47.5719 mL |
| 5 mM | 0.3806 mL | 1.9029 mL | 3.8058 mL | 9.5144 mL | |
| 10 mM | 0.1903 mL | 0.9514 mL | 1.9029 mL | 4.7572 mL | |
| 15 mM | 0.1269 mL | 0.6343 mL | 1.2686 mL | 3.1715 mL | |
| 20 mM | 0.0951 mL | 0.4757 mL | 0.9514 mL | 2.3786 mL | |
| 25 mM | 0.0761 mL | 0.3806 mL | 0.7612 mL | 1.9029 mL | |
| 30 mM | 0.0634 mL | 0.3171 mL | 0.6343 mL | 1.5857 mL | |
| 40 mM | 0.0476 mL | 0.2379 mL | 0.4757 mL | 1.1893 mL | |
| 50 mM | 0.0381 mL | 0.1903 mL | 0.3806 mL | 0.9514 mL | |
| 60 mM | 0.0317 mL | 0.1586 mL | 0.3171 mL | 0.7929 mL | |
| 80 mM | 0.0238 mL | 0.1189 mL | 0.2379 mL | 0.5946 mL | |
| 100 mM | 0.0190 mL | 0.0951 mL | 0.1903 mL | 0.4757 mL |
GSK9027 Related Classifications
HY-103548 Related Classifications
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