1815580-06-3
1815580-06-3
Chemical Structure
SKLB-23bb
- CAS No.: 1815580-06-3
- Formula:C21H24N4O4
- Molecular Weight:396.44
IUPAC Name: N-hydroxy-4-(2-methoxy-5-(methyl(2-methylquinazolin-4-yl)amino)phenoxy)butanamide
InChIKey: FWXZZFONXWYSEF-UHFFFAOYSA-N
SMILES: CN(C1=CC(OCCCC(NO)=O)=C(OC)C=C1)C2=NC(C)=NC3=CC=CC=C32
Biological Activity: SKLB-23bb is a potent and selective inhibitor for HDAC6 with an IC50 of 17 nM and shows 25-fold and 200-fold selectivity relative to HDAC1 (IC50=422 nM) and HDAC8 (IC50=3398 nM), respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SKLB-23bb | 98.0% | SKLB-23bb is a potent and selective inhibitor for HDAC6 with an IC50 of 17 nM and shows 25-fold and 200-fold selectivity relative to HDAC1 (IC50=422 nM) and HDAC8 (IC50=3398 nM), respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
