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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
51 Results for "
hypoglycemic effects
" in MedChemExpress (MCE) Product Catalog:
Products (51)
51 Results for "hypoglycemic effects" in MCE Product Catalog:
Cat. No.: HY-N5086
CAS No.: 211567-04-3
Category:
Neurological Disease Metabolic Disease Plants Monophenols Iridoids Terpenoids Scrophulariaceae Phenols Picrorhiza scrophulariiflora Pennell Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-B0089R
CAS No.: 56180-94-0
Synonyms: BAY g 5421 (Standard)
Category:
Target:
Cat. No.: HY-W1113135
CAS No.: 2828447-14-7
Target:
Research Areas:
Carboxymethyl-β-cyclodextrin sodium salt is a negatively charged β-cyclodextrin derivative, as well as a metal ion chelator and solubilizing reagent. Carboxymethyl-β-cyclodextrin sodium salt forms stable aqueous complexes with Ba 2+, Ca 2+, Cd 2+, Ni 2+, Pb 2+, Sr 2+, and Zn 2+ ions. Carboxymethyl-β-cyclodextrin sodium salt derived hydrogel carriers support oral insulin delivery via paracellular permeation across Caco-2 monolayers and produce sustained hypoglycemic effects in diabetic mice. Carboxymethyl-β-cyclodextrin sodium salt can be conjugated onto folate-modified BSA nanoparticles to boost folate receptor-mediated endocytosis, elevate intracellular anticancer drug uptake and trigger cell apoptosis. Carboxymethyl-β-cyclodextrin sodium salt can be utilized for chiral separation in capillary electrophoresis, development of nanoscale drug carriers and nucleic acid transfection research .
Category:
Iridoids Terpenoids Scrophulariaceae Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey
Target:
Cat. No.: HY-105935R
CAS No.: 18719-76-1
Synonyms: Cyanidin 3-rutinoside chloride (Standard); Cyanidin 3-O-rutinoside chloride (Standard); Sambucin chloride (Standard)
Cat. No.: HY-172120
CAS No.: 2097502-14-0
Target:
Research Areas:
GPR119 agonist 3 (Compound 21b) is an orally active agonist of GPR119 with an EC50 value of 3.8 nM for hGPR119. Additionally, GPR119 agonist 3 exhibits hypoglycemic effects and can be used in research on type 2 diabetes and obesity .
Cat. No.: HY-170692
Research Areas:
Hypoglycemic agent 3 (Compound H26), a derivative of corosolic acid, exhibits lipid-lowering and significant hypoglycemic effects and can be used as a hypoglycemic agent. Hypoglycemic agent 3 inhibits insulin resistance by targeting MCCC1 and can be used in the study of type 2 diabetes .
Cat. No.: HY-N12647
CAS No.: 230292-85-0
Target:
Cat. No.: HY-B0089A
CAS No.: 1221158-13-9
Synonyms: Bay-g 5421 sulfate
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Cat. No.: HY-162758
Target:
Research Areas:
ALR2-IN-5 (Compound 10a) is an inhibitor of ALR2 with an IC50 value of 99.29 nM. ALR2-IN-5 exhibits hypoglycemic effects and can be utilized in research related to diabetes .
Cat. No.: HY-N12543
CAS No.: 27539-32-8
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Cat. No.: HY-121323R
CAS No.: 4430-36-8
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Research Areas:
Acarbose (Standard) is the analytical standard of Acarbose. This product is intended for research and analytical applications. Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .
Cat. No.: HY-117985A
CAS No.: 1246960-27-9
Synonyms: DA-1229 hydrochloride
Target:
Research Areas:
Evogliptin hydrochloride (DA-1229 hydrochloride) is an orally available DPP4 inhibitor with significant and durable hypoglycemic effects in mouse models. Evogliptin hydrochloride also inhibits the generation of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin hydrochloride can be used in the research of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation .
Cat. No.: HY-B0089S
CAS No.: 1260619-60-0
Synonyms: BAY g 5421-d4
Cat. No.: HY-N0655R
CAS No.: 10284-63-6
Synonyms: 3-O-Methyl-D-chiro-inositol (Standard)
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Cat. No.: HY-173503
CAS No.: 1598439-44-1
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Research Areas:
DS-1150b is an orally active GLUT4 activator. DS-1150b has the activity of activating GLUT4 transport and can promote the translocation of GLUT4 to the cell membrane in skeletal muscle cells. DS-1150b has shown hypoglycemic effects in the Zucker obese rat model and can be used in the study of type 2 diabetes mellitus (T2DM) .
Cat. No.: HY-175263
CAS No.: 38239-51-9
Research Areas:
Aminochalcone 4AAF is a neuroprotective agent that exerts anxiolytic effects through GABAA and 5-HT receptors. Aminochalcone 4AAF has high selectivity for 5-HT3A and 5-HT2C receptors, and stimulates allosteric behavior toward the 5-HT2A receptor. Aminochalcone 4AAF shows hypoglycemic effects and reduces the level of ROS in the liver. Aminochalcone 4AAF delays the clonic stage of the epileptic seizures . Aminochalcone 4AAF can be used in the study of anxiety, hyperglycemia, and seizures .
Cat. No.: HY-173217
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Research Areas:
PPARα agonist 5 is an orally available, selective partial agonist of PPARα (EC50: 3 nM). PPARα agonist 5 reduces lipid accumulation and upregulates key PPARα target genes, exerting anti-fatty liver effects. PPARα agonist 5 also exhibits significant hypolipidemic and hypoglycemic effects through partial PPARγ agonist activity and mild inhibition of protein tyrosine phosphatase 1B (PTP1B) (IC50: 79.1 μM). PPARα agonist 5 has a good safety profile and can be used in the study of type 2 diabetes with dyslipidemia .
Cat. No.: HY-N5083R
CAS No.: 20310-89-8
Cat. No.: HY-126969
CAS No.: 870095-15-1
Target:
Research Areas:
C333H is a selective PPARγ modulator with insulin-sensitizing and hypoglycemic activities. C333H exhibits similar insulin-sensitizing effects to thiazolidinediones (TZDs) in diabetic mouse models without significantly increasing body weight or adipose tissue weight. C333H increases circulating high molecular weight adiponectin isoform levels in diabetic db/db mice, reduces serine phosphorylation of PPARγ 273 in brown adipose tissue, and selectively modulates the expression of specific PPARγ target genes in adipose tissue. Express. C333H exhibits weak recruitment of co-activators and weak dissociation of co-repressors in vitro. These properties suggest that C333H may be a potential inhibitor of type 2 diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
