1246960-27-9
Chemical Structure
Evogliptin hydrochloride
Synonym(s): DA-1229 hydrochloride
- CAS No.: 1246960-27-9
- Formula:C19H27ClF3N3O3
- Molecular Weight:437.88
IUPAC Name: (R)-4-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazin-2-one hydrochloride
InChIKey: QHQXWMKKQNSBTC-VQZRABBESA-N
SMILES: O=C1NCCN([C@@H]1COC(C)(C)C)C(C[C@@H](CC2=CC(F)=C(C=C2F)F)N)=O.Cl
Biological Activity: Evogliptin hydrochloride (DA-1229 hydrochloride) is an orally available DPP4 inhibitor with significant and durable hypoglycemic effects in mouse models. Evogliptin hydrochloride also inhibits the generation of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin hydrochloride can be used in the research of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Evogliptin hydrochloride | Evogliptin hydrochloride (DA-1229 hydrochloride) is an orally available DPP4 inhibitor with significant and durable hypoglycemic effects in mouse models. Evogliptin hydrochloride also inhibits the generation of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin hydrochloride can be used in the research of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
