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Cat. No.: HY-117985A

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Evogliptin hydrochloride

Name: Evogliptin hydrochloride
Brand: MedChemExpress
SKU: HY-117985A
Availability: PreOrder

(Synonyms: DA-1229 hydrochloride)

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Evogliptin hydrochloride (DA-1229 hydrochloride) is an orally available DPP4 inhibitor with significant and durable hypoglycemic effects in mouse models. Evogliptin hydrochloride also inhibits the generation of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin hydrochloride can be used in the research of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation.

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CAS No.: 1246960-27-9
Formule: C₁₉H₂₇ClF₃N₃O₃
Masse moléculaire:437.88

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Evogliptin hydrochloride Chemical Structure

CAS No.: 1246960-27-9

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Description

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Chemical Information

CAS No. 1246960-27-9
Masse moléculaire 437.88
Formule C₁₉H₂₇ClF₃N₃O₃
SMILES

O=C1NCCN([C@@H]1COC(C)(C)C)C(C[C@@H](CC2=CC(F)=C(C=C2F)F)N)=O.Cl
Synonyms

DA-1229 hydrochloride
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Cell Rep

Aortic valve stenosis serum IGFBP2 mediates female-specific Evogliptin resistance in valve myofibroblasts. [Abstract]

2026 Jul 13;45(7):117678. PMID: 42441401
bioRxiv

Circulating biomarkers in serum from aortic valve stenosis patients predict sex-specific drug responses in valve myofibroblasts. [Abstract]

2026 Jan 20:2026.01.16.700010. PMID: 41648356

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Kim M K, et al. Prevention and treatment effect of evogliptin on hepatic steatosis in high-fat-fed animal models[J]. Archives of pharmacal research, 2017, 40(2): 268-281. [Content Brief]

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Evogliptin hydrochloride

2 Cited Publications

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Evogliptin hydrochloride

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Publications Citing Use of MedChemExpress (MCE) Evogliptin hydrochloride

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