61 Results for "

peptide coupling

" in MedChemExpress (MCE) Product Catalog:
Products (61)

61 Results for "peptide coupling" in MCE Product Catalog:

Cat. No.: HY-158199
CAS No.: 2126749-95-7
Target:  

ADC Linkers

Research Areas:  

Cancer

BCN-HS-PEG2-bis(PNP) is a p-nitrophenyl ADC linker that can be used for further coupling of ADC toxins with peptide linkers. BCN-HS-PEG2-bis(PNP) can be combined with vc-PABC-MMAE (HY-15162) to form drug-linker conjugates for ADCs.
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Cat. No.: HY-P2398
CAS No.: 878797-01-4
Research Areas:  

Others

Fmoc-Phe-Ser(psi(Me,Me)pro)-OH is a pseudo-proline dipeptide building block corresponding to positions 27-28 of the teduglutide sequence. Fmoc-Phe-Ser(psi(Me,Me)pro)-OH is applied in solid-phase peptide synthesis. Fmoc-Phe-Ser(psi(Me,Me)pro)-OH can be used for the research of teduglutide synthesis .
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Cat. No.: HY-151782
CAS No.: 2250437-45-5
Target:  

ADC Linkers

Research Areas:  

Others

The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction. Polyglycine fragments containing up to 7 glycines are reported to bind to surfaces and have potential application in nanotechnology constructs: constructs of Gly7-NHCH2-fragment containing peptides bind on mica surface in aqueous solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Cat. No.: HY-P11023
E16-uPA24 is a chimeric peptide targeting urokinase-type plasminogen activator receptor (uPAR). E16-uPA24 modifies senescent cells surface with polyglutamic acid, promoting immune cell-mediated responses through glutamate recognition. E16-uPA24 induces immune clearance of senescent cells and restores tissue homeostasis by enhancing immune cells recruitment and directly coupling senescent cells and immune cells. E16-uPA24 can be used for tissue degeneration, chronic inflammatory disease and age-related tumorigenesis research .
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Cat. No.: HY-P11428
CAS No.: 2425606-55-7
Research Areas:  

Others

DBCO-cyclo (RGDfK) is a clickable DBCO-modified cyclic RGD peptide, and also a DBCO derivative of cyclo (RGDfK) (HY-P0023). DBCO-cyclo (RGDfK) is synthesized via an amide coupling reaction between DBCO-NHS ester and cyclo (RGDfK). DBCO-cyclo (RGDfK) can react with azide groups through copper-free click chemistry (SPAAC) to immobilize RGD peptides onto biomaterials or hydrogels. The RGD sequence in DBCO-cyclo (RGDfK) is recognizable by cellular integrins and promotes cell adhesion. DBCO-cyclo (RGDfK) can be used in studies related to tissue engineering, 3D cell culture, and surface functionalization of biomaterials .
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Cat. No.: HY-W441014A
Research Areas:  

Others

DSPE-PEG10000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .
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Cat. No.: HY-W283556
CAS No.: 162148-48-3
DO2A-tert-butyl ester is a bifunctional chelator (BFC) that can be used for the coupling of peptides and radionuclides. DO2A-tert-butyl ester can be used in the development of radionuclide imaging tracers .
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Cat. No.: HY-174358D
CAS No.: 39927-08-7
HOOC-PEG10000-COOH has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG10000-COOH is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .
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Cat. No.: HY-P2392
CAS No.: 252554-79-3
Research Areas:  

Others

Fmoc-Ala-Thr (psi (Me,Me) pro)-OH is an Fmoc-protected pseudoproline derivative that serves as a building block for solid-phase peptide synthesis. Fmoc-Ala-Thr (psi (Me,Me) pro)-OH inhibits polypeptide aggregation and improves amino acid coupling efficiency during the synthesis of human and rat IAPP as well as general peptide synthesis. Fmoc-Ala-Thr (psi (Me,Me) pro)-OH is applicable to peptide synthesis-related research .
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Cat. No.: HY-79880R
CAS No.: 530-62-1
Synonyms: 1,1'-Carbonyldiimidazole (Standard)
Research Areas:  

Others

N,N'-Carbonyldiimidazole (Standard) (1,1'-Carbonyldiimidazole (Standard)) is the analytical standard of N,N'-Carbonyldiimidazole (HY-79880). This product is intended for research and analytical applications. N,N'-Carbonyldiimidazole (1,1'-Carbonyldiimidazole) is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. N,N'-Carbonyldiimidazole can be used as a coupling agent and a peptide synthesis reagent .
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Cat. No.: HY-118112
CAS No.: 64191-06-6
Research Areas:  

Others

4-N-Maleimidobenzoicacid-NHS is a PEG linker that finds utility in bioconjugation endeavors and protein labeling ventures. Specifically designed for selective reaction with thiol groups, the maleimide group establishes covalent linkages, thereby facilitating the coupling of proteins, peptides, or diverse molecules to thiol-bearing biomolecules. The NHS ester is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic conditions to form a covalent bond.
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Cat. No.: HY-148031
CAS No.: 1638970-45-2
Target:  

ADC Linkers

Research Areas:  

Others

MC-Ala-Ala-Asn-PAB-PNP is a peptide, can be used to synthesize specifically activated micromolecular target coupling body .
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Cat. No.: HY-120286
CAS No.: 108890-90-0
K-13 is a cyclic peptide compound synthesized by a specific organozinc reagent. Its synthesis process involves intermolecular and intramolecular Negishi cross-coupling reactions and is one of the shortest routes reported for the synthesis of such cyclic peptides.
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Cat. No.: HY-78824
CAS No.: 128421-85-2
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Glycine, N-[(1,1-dimethylethoxy)carbonyl]thio-L-phenylalanyl-, methyl ester (compound 3b) is a polypeptide compound containing sulfamide, can be used to synthesis peptide-agent coupling compounds .
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Cat. No.: HY-174358A
CAS No.: 39927-08-7
HOOC-PEG2000-COOH has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG2000-COOH is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .
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Cat. No.: HY-174358E
CAS No.: 39927-08-7
HOOC-PEG20000-COOH has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG20000-COOH is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .
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Cat. No.: HY-149117
CAS No.: 467233-94-9
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
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Cat. No.: HY-130282
CAS No.: 1643593-30-9
Target:  

Bacterial

Research Areas:  

Infection

Ianthelliformisamine C ditrifluoroacetate is an antibiotic enhancer with activity against resistant Gram-negative bacteria. Ianthelliformisamine C ditrifluoroacetate has been shown to improve the efficacy of doxycycline against Pseudomonas aeruginosa. Ianthelliformisamine C ditrifluoroacetate was prepared using peptide coupling, resulting in high chemical yields of 27 to 91%. Ianthelliformisamine C ditrifluoroacetate exhibits its mechanism of action by inducing ATP efflux and causing membrane depolarization in bacterial cells.
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Cat. No.: HY-P10306
Target:  

Bacterial

Research Areas:  

Infection

Cys-LL37 is a biomaterial with antimicrobial properties developed by covalently fixing to the surface of titanium. Cys-LL37 uses a flexible hydrophilic polyethylene glycol spacer and selective n-terminal coupling LL37, a surface peptide layer that kills bacteria on contact is formed. Cys-LL37 can be used in research to develop new antimicrobial biomaterials .
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Cat. No.: HY-174961
Synonyms: Fmoc-NH-PEG1000-Mal
Fmoc-PEG1000-Maleimide (Fmoc-NH-PEG1000-Mal) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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