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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
recombinant DNA
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "recombinant DNA" in MCE Product Catalog:
Cat. No.: HY-E70583
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Recombinant Ten-Eleven Translocase is a recombinant Fe(II)- and α-ketoglutarate-dependent dioxygenase. Recombinant Ten-Eleven Translocase converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), and then to 5-formylcytosine (5fC) and 5-carboxycytosine (5caC) through a series of oxidation reactions. Then, 5caC is further converted into uracil (U) through the action of a conversion agent or enzyme, and uracil (U) is converted into thymine (T) through PCR, thereby achieving single-base resolution and high-accuracy identification of DNA methylation sites .
Cat. No.: HY-W012817R
CAS No.: 95-71-6
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Cat. No.: HY-W015892R
CAS No.: 695-06-7
Synonyms: γ-Caprolactone (Standard)
Category:
Cat. No.: HY-E71731
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Research Areas:
AlkB (RNA/DNA demethylase, Nuclease-free) is a recombinant repair and editing enzyme that removes alkylation damage and specific methyl groups from nucleic acids without degrading them. AlkB (RNA/DNA demethylase, Nuclease-free) targets modifications like m¹A, m³C, or m¹G in RNA and DNA, and is supplied free of contaminating DNase and RNase activities.
Cat. No.: HY-E72103
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Research Areas:
Human CYP1A1, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 1A1, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP1A1 is a human cytochrome P450 subtype belonging to the CYP1 family, as well as a major metabolic enzyme. Its expression is concentrated in tissues such as lung, breast, placenta and endometrium, and it can metabolize polycyclic aromatic hydrocarbons and estrogens into carcinogenic intermediates with DNA-damaging activity .
Cat. No.: HY-183831
CAS No.: 3034312-19-8
GPS167 is a CLK kinase inhibitor that potently and selectively inhibits recombinant human CLK1, CLK2 and CLK4. By inhibiting CLK-mediated phosphorylation of SRSF10, GPS167 upregulates the protein-binding ability of CLK1 and CLK4 with SRSF10, downregulates oncogenic BCLAF1-L and upregulates tumor-suppressive BCLAF1-S, regulates alternative splicing of genes such as MDM2 and MDM4, stabilizes p53 protein and induces DNA damage, ultimately triggering tumor cell apoptosis. GPS167 can block the epithelial-mesenchymal transition process of tumors, activate intracellular double-stranded RNA-mediated antiviral immune responses, and produce synergistic cytotoxicity when combined with microtubule-targeting drugs. GPS167 can be used in research related to various cancers including colorectal cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
