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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
53 Results for "
splicing factor
" in MedChemExpress (MCE) Product Catalog:
Products (53)
53 Results for "splicing factor" in MCE Product Catalog:
製品番号: HY-P72056
純度: ≥ 90%, as determined by reducing SDS-PAGE.
別名: TRA2B; TRA-2 Beta; Prev. SFRS10; Transformer 2 Beta Homolog (Drosophila); Htra2-Beta; HTRA2-Beta; PPP1R156; TRA2-BETA; splicing factor, Arginine/Serine-Rich 10 (Transformer 2 Homolog, Drosophila); TRA2-Beta; Protein Phosphatase 1, Regulatory Subunit 156;
Species:
Human
Source:
Sf9 insect cells
製品番号: HY-185928
CAS 番号: 2659211-29-5
Target:
研究分野:
Pinzodirsen (Compound ENTR-Oligo-0034) is a dystrophia myotonica protein kinase (DMPK) steric blocker. Pinzodirsen reduces the nuclear sequestration of toxic DMPK mRNA with splicing factors such as MBNL1 via steric blocking/relocation, or interferes with the secondary structure of CUG repeat RNA, instead of being cleaved by RNase H, thereby ameliorating systemic aberrant splicing in DM1. Pinzodirsen is applicable to the research of myotonic dystrophy .
製品番号: HY-147262D
Target:
Antibody-Oligonucleotide Conjugates (AOCs) Small Interfering RNA (siRNA) Myotonin-Protein Kinase (DMPK)
研究分野:
Unconjugated/naked Etedesiran (without SMCC linker) is a small interfering RNA (siRNA) targeting DMPK, and also represents the unconjugated, non-SMCC linker-bound component of delpacibart etedesiran. Unconjugated/naked Etedesiran (without SMCC linker) corrects pathogenic mRNA aberrant splicing by targeting and degrading mutant DMPK mRNA, thereby releasing sequestered MBNL splicing factors. Unconjugated/naked Etedesiran (without SMCC linker) can be used in studies of myotonic dystrophy type 1 .
製品番号: HY-P701567
純度: ≥ 90%, as determined by reducing SDS-PAGE.
別名: SF3B3; STAF130; splicing factor 3b Subunit 3; SAP 130; SF3b130; Pre-MRNA splicing factor SF3b, 130 KDa Subunit; SAP130; Pre-MRNA-splicing factor SF3b 130 KDa Subunit; Spliceosome-Associated Protein 130; splicing factor 3b, Subunit 3, 130kDa; KIAA0017; Spl
Species:
Human
Source:
Sf9 insect cells
製品番号: HY-P701566
純度: ≥ 90%, as determined by reducing SDS-PAGE.
別名: SF3B3; STAF130; splicing factor 3b Subunit 3; SAP 130; SF3b130; Pre-MRNA splicing factor SF3b, 130 KDa Subunit; SAP130; Pre-MRNA-splicing factor SF3b 130 KDa Subunit; Spliceosome-Associated Protein 130; splicing factor 3b, Subunit 3, 130kDa; KIAA0017; Spl
Species:
Human
Source:
Sf9 insect cells
製品番号: HY-P703348
純度: ≥ 95%, as determined by reducing SDS-PAGE.
別名: SUGP1; F23858; Prev. SF4; RNA-Binding Protein RBP; splicing factor 4; DKFZp434E2216; SURP And G-Patch Domain-Containing Protein 1; CDNA FLJ57089, Highly Similar To splicing factor 4; SURP And G-Patch Domain Containing 1; RBP
Species:
Human
Source:
E. coli
製品番号: HY-P73635
純度: ≥ 85%, as determined by reducing SDS-PAGE.
別名: SMNDC1; Survival Of Motor Neuron-Related-splicing factor 30; Survival Motor Neuron Domain Containing 1; Survival Motor Neuron Domain-Containing Protein 1; SPF30; 30 KDa splicing factor SMNrp; SMNR; Tudor Domain Containing 16C; TDRD16C; SMN-Related Protein
Species:
Human
Source:
E. coli
製品番号: HY-104040R
CAS 番号: 1338934-59-0
別名: Orin1001 (Standard)
Target:
研究分野:
MKC8866 (Standard) is the analytical standard of MKC8866 (HY-104040). This product is intended for research and analytical applications. MKC8866, a salicylaldehyde analog, is a potent, selective IRE1 RNase inhibitor with an IC50 of 0.29 μM in human vitro. MKC8866 strongly inhibits Dithiothreitol-induced X-box-binding protein 1-spliced (XBP1s) expression with an EC50 of 0.52 μM and unstresses RPMI 8226 cells with an IC50 of 0.14 μM . MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibits prostate cancer (PCa) tumor growth .
製品番号: HY-P81426A
別名: SF3B3; KIAA0017; SAP130; splicing factor 3B subunit 3; Pre-mRNA-splicing factor SF3b 130 kDa subunit; SF3b130; STAF130; Spliceosome-associated protein 130; SAP 130
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
