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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
151 Results for "
5-Hydroxytryptamine
" in MedChemExpress (MCE) Product Catalog:
Products (151)
151 Results for "5-Hydroxytryptamine" in MCE Product Catalog:
Cat. No.: HY-W010973S
CAS No.: 2687960-56-9
Research Areas:
5-Hydroxytryptamine-d4 creatinine sulfate monohydrate is the deuterated-labeled 5-Hydroxytryptamine creatinine sulfate monohydrate (HY-W010973). 5-Hydroxytryptamine creatinine sulfate monohydrate is a 5-HT receptor agonist and amine oxidase substrate that acts through multiple physiological responses, including induction of vasoconstriction, pressor effects, acceleration of platelet potassium exchange, and endothelium-dependent relaxation, and can serve as a radiolabeled substrate for organelle uptake assays. 5-Hydroxytryptamine creatinine sulfate monohydrate can be used in research on burns, tourniquet and botulinum shock .
Cat. No.: HY-B1473S2
CAS No.: 1269486-67-0
Synonyms: 5-Hydroxytryptamine-13C,D4; 5-HT-13C,D4
Cat. No.: HY-15414AR
CAS No.: 960203-27-4
Synonyms: Lu AA21004 hydrobromide (Standard)
Research Areas:
Vortioxetine (hydrobromide) (Standard) is the analytical standard of Vortioxetine (hydrobromide). This product is intended for research and analytical applications. Vortioxetine (Lu AA 21004) hydrobromide is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial 5-HT1B agonist (Ki: 15 nM, 33 nM) .
Cat. No.: HY-15414S
CAS No.: 2140316-62-5
Synonyms: Lu AA 21004 d8
Cat. No.: HY-156807
CAS No.: 210751-39-6
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LY 367265 is a 5-hydroxytryptamine transporter (SERT) inhibitor (IC₅₀ = 3.1 nM) and a 5-HT₂A receptor antagonist (Kᵢ = 0.81 nM). LY 367265 has the inhibitory activity on the norepinephrine transporter (NET) of extremely weak (IC₅₀ > 1000 nM); it has low affinity for subtypes such as 5-HT₁B (Kᵢ = 490 nM) and 5-HT₁D (Kᵢ = 81 nM), showing high selectivity. LY 367265 concentration-dependently enhances of [³H]5-HT efflux (EC₅₀ = 250 nM). LY 367265 antagonizes the contraction response of Sumatriptan (HY-B0121B), indicating its functional antagonistic activity on 5-HT₁D-like receptors. LY 367265 can be used for the study of diseases such as anxiety disorders and post-traumatic stress disorder .
Cat. No.: HY-107854R
CAS No.: 1210-83-9
Synonyms: N-Acetylserotonin (Standard); Normelatonin (Standard); O-Demethylmelatonin (Standard)
Cat. No.: HY-W010973R
CAS No.: 61-47-2
Cat. No.: HY-106605
CAS No.: 61325-80-2
Synonyms: LY 120363
Target:
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Flumezapine (LY 120363) is a potent and balanced antagonist of the dopamine D2 receptor and the 5-hydroxytryptamine receptor (5-HT receptor). Flumezapine does not alter the increase in serum cortisol caused by κ-opioid receptor agonists. Flumezapine inhibits the conditioned avoidance response in rats and has a low risk of extrapyramidal side effects. Flumezapine can be used in antipsychotic research .
Cat. No.: HY-W399186
CAS No.: 5527-71-9
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Methylclonazepam is a benzodiazepine with anxiolytic activity. Methylclonazepam inhibits the absorption of 5-hydroxytryptamine by Schistosoma mansoni. Methylclonazepam derivatives have anti-Schistosoma mansoni activity .
Cat. No.: HY-19358B
CAS No.: 78263-91-9
Synonyms: 2-Methyl-5-Hydroxytryptamine maleate; 2-Methylserotonin maleate; 2-Me-HT maleate
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2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT maleate is shown to display anti-depressive-like effects .
Cat. No.: HY-W740297
CAS No.: 1189992-73-1
Cat. No.: HY-A0019AS
CAS No.: 1794685-21-4
Synonyms: 9-Hydroxyrisperidone palmitate-d4
Cat. No.: HY-10351
CAS No.: 169758-66-1
Synonyms: NAD-299
Target:
Research Areas:
Robalzotan (NAD-299) is a potent and selective 5-Hydroxytryptamine 1A (5-HT1A) inhibitor. Robalzotan increases the firing rate of 5-HT cells. Robalzotan induces 5-HT1A receptor occupancy. Robalzotan has the potential for the research of a cholinergic deficit in the central -nervous system .
Cat. No.: HY-13051
CAS No.: 630407-66-8
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SB-773812 is a moderate-affinity antagonist at dopamine receptor 2 (pKi=7.4) and a high-affinity antagonist at the dopamine receptor 3 (pKi=8.5) and at the serotonin 5-hydroxytryptamine receptors 2A (pKi=9.0), 2C (pKi=8.1), and 6 (pKi=8.1). SB-773812 is promising for research of central nervous system disorders .
Cat. No.: HY-19046
CAS No.: 103353-87-3
Synonyms: SC 48274 hydrochloride; BTG 1501 hydrochloride
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AGN‑2979 hydrochloride (SC 48274 hydrochloride; BTG 1501 hydrochloride) is an orally active and selective tryptophan hydroxylase inhibitor with antidepressant-like and anxiolytic-like activities. AGN‑2979 hydrochloride inhibits stress-induced activation of tryptophan hydroxylase, thereby limiting the biosynthesis of 5-hydroxytryptamine in the brain. AGN-2979 hydrochloride possesses non-sedative anxiolytic and cognitive-enhancing properties. AGN-2979 hydrochloride is applicable to research related to depression and generalized anxiety disorder .
Cat. No.: HY-W1123900
CAS No.: 2945111-66-8
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Research Areas:
5-HT2A agonist 3 (Compound P-141) is a selective 5-hydroxytryptamine 2A receptor (5-HT2A) agonist with an EC50 value of 13.80 nM. 5-HT2A agonist 3 is promising for research of mental illnesses such as depression, post-traumatic stress disorder, obsessive-compulsive disorder, and central nervous system disorders .
Cat. No.: HY-15414AS
Synonyms: Lu AA21004-d8 hydrobromide
Cat. No.: HY-12390A
CAS No.: 26786-32-3
Synonyms: Lopramine hydrochloride
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Research Areas:
Lofepramine (Lopramine) is a modified tricyclic and orally active antidepressant. Lofepramine inhibits the uptake of Noradrenaline (NA) (HY-13715) and 5-hydroxytryptamine (5-HT) with IC50s of 2.7 μM and 11 μM, respectively. Lofepramine exerts its antidepressant activity by promoting noradrenergic neurotransmission. Lofepramine also enhances serotonergic neurotransmission by inhibiting neuronal uptake of 5-HT and tryptophan pyrrolase. Lofepramine exhibits significant anxiolytic properties. .
Cat. No.: HY-169611
CAS No.: 18525-25-2
Synonyms: 5-Hydroxytryptamine maleate; 5-HT maleate
Target:
Research Areas:
Serotonin hydrogen maleate is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrogen maleate is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
