103353-87-3
Chemical Structure
AGN-2979 hydrochloride
Synonym(s): SC 48274 hydrochloride; BTG 1501 hydrochloride
- CAS No.: 103353-87-3
- Formula:C19H29ClN2O3
- Molecular Weight:368.90
IUPAC Name: 3-(3-(dimethylamino)propyl)-3-(3-methoxyphenyl)-4,4-dimethylpiperidine-2,6-dione hydrochloride
InChIKey: WCDCKCAPKMUVHY-UHFFFAOYSA-N
SMILES: O=C(C(C1=CC=CC(OC)=C1)(CCCN(C)C)C(C)(C)C2)NC2=O.Cl
Biological Activity: AGN‑2979 hydrochloride (SC 48274 hydrochloride; BTG 1501 hydrochloride) is an orally active and selective tryptophan hydroxylase inhibitor with antidepressant-like and anxiolytic-like activities. AGN‑2979 hydrochloride inhibits stress-induced activation of tryptophan hydroxylase, thereby limiting the biosynthesis of 5-hydroxytryptamine in the brain. AGN-2979 hydrochloride possesses non-sedative anxiolytic and cognitive-enhancing properties. AGN-2979 hydrochloride is applicable to research related to depression and generalized anxiety disorder[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
AGN-2979 hydrochloride | AGN‑2979 hydrochloride (SC 48274 hydrochloride; BTG 1501 hydrochloride) is an orally active and selective tryptophan hydroxylase inhibitor with antidepressant-like and anxiolytic-like activities. AGN‑2979 hydrochloride inhibits stress-induced activation of tryptophan hydroxylase, thereby limiting the biosynthesis of 5-hydroxytryptamine in the brain. AGN-2979 hydrochloride possesses non-sedative anxiolytic and cognitive-enhancing properties. AGN-2979 hydrochloride is applicable to research related to depression and generalized anxiety disorder. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Gittos MW, et al. Antidepressant-like action of AGN 2979, a tryptophan hydroxylase activation inhibitor, in a chronic mild stress model of depression in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 2001 Oct;11(5):351-7. [Content Brief]
