103353-87-3
103353-87-3
Chemical Structure
AGN-2979 hydrochloride
Synonym(s): SC 48274 hydrochloride
- CAS No.: 103353-87-3
- Formula:C19H29ClN2O3
- Molecular Weight:368.90
IUPAC Name: 3-(3-(dimethylamino)propyl)-3-(3-methoxyphenyl)-4,4-dimethylpiperidine-2,6-dione hydrochloride
InChIKey: WCDCKCAPKMUVHY-UHFFFAOYSA-N
SMILES: O=C(C(C1=CC=CC(OC)=C1)(CCCN(C)C)C(C)(C)C2)NC2=O.Cl
Biological Activity: AGN-2979 (SC 48274) hydrochloride is a tryptophan hydroxylase activation inhibitor. AGN-2979 hydrochloride exhibits antidepressant and anxiolytic activities[1][2].
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AGN-2979 hydrochloride | AGN-2979 (SC 48274) hydrochloride is a tryptophan hydroxylase activation inhibitor. AGN-2979 hydrochloride exhibits antidepressant and anxiolytic activities. | |||||||||||||||||||||
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References
- [1]. Gittos MW, et al. Antidepressant-like action of AGN 2979, a tryptophan hydroxylase activation inhibitor, in a chronic mild stress model of depression in rats. Eur Neuropsychopharmacol. 2001 Oct;11(5):351-7. [Content Brief]
- [2]. Ogawa N, et al. Anxiolytic activity of SC-48274 compared with those of buspirone and diazepam in experimental anxiety models. Jpn J Pharmacol. 1993 Feb;61(2):115-21. [Content Brief]
Keywords
