56-69-9
56-69-9
Chemical Structure
5-Hydroxytryptophan
Synonym(s): 5-HTP; DL-5-Hydroxytryptophan
- CAS No.: 56-69-9
- Formula:C11H12N2O3
- Molecular Weight:220.23
IUPAC Name: 2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
InChIKey: LDCYZAJDBXYCGN-UHFFFAOYSA-N
SMILES: NC(CC1=CNC2=CC=C(O)C=C12)C(O)=O
Biological Activity: 5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. [1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5-Hydroxytryptophan | 99.89% | 5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. . | ||||||||||||||||||||
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5-Hydroxytryptophan (Standard) | 99.68% | 5-Hydroxytryptophan (Standard) is the analytical standard of 5-Hydroxytryptophan. This product is intended for research and analytical applications. 5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. . | ||||||||||||||||||||
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5-Methoxy-DL-tryptophan | 98.73% | 5-Methoxy-DL-tryptophan is a metabolite. 5-Methoxy-DL-tryptophan reduces LPS (HY-D1056)-induced release of IL-6. 5-Methoxy-DL-tryptophan has anti-inflammatory effects. 5-Methoxy-DL-tryptophan can be used in the study of atherosclerosis. | ||||||||||||||||||||
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5-Bromo-L-tryptophan | 99.61% | 5-Bromo-L-tryptophan is a substrate of PLP-dependent enzyme AetE, as well as an indole alkaloid and Amino acid derivative. 5-Bromo-L-tryptophan can be isolated from Semenospongia sp. 5-Bromo-L-tryptophan can be converted into 5-bromoindole (HY-30236) via AetE-mediated catalysis. 5-Bromo-L-tryptophan is applicable to colon cancer research. | ||||||||||||||||||||
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6-Bromo-L-tryptophan | 99.44% | 6-Bromo-L-tryptophan (6BrW) is a compound that can be incorporated into recombinant proteins by a specific system in bacterial cells, causing a blue shift in fluorescence emission and absorption maxima. | ||||||||||||||||||||
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5-Fluoro-L-tryptophan | 99.99% | 5-Fluoro-L-tryptophan is a competitive vesicular glutamate transporter (VGLUT) inhibitor. 5-Fluoro-L-tryptophan is promising for research of diseases associated with the neurotransmitter systems. | ||||||||||||||||||||
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5-Methyl-DL-tryptophan | 99.94% | 5-Methyl-DL-tryptophan is an orally active amino acid derivative with anti-inflammatory signaling effects. 5-Methyl-DL-tryptophan inhibits TLR4/MyD88 signaling and NF-κB activation/phosphorylation, reduces IL-6/IL-1β/TNF-α, and decreases the p-p65/p65 ratio. 5-Methyl-DL-tryptophan inhibits anthranilate synthase (Ki = 13 μM). 5-Methyl-DL-tryptophan inhibits bacterial growth. 5-Methyl-DL-tryptophan can be used in research on ulcerative colitis. | ||||||||||||||||||||
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L-5-Hydroxytryptophan | 99.99% | L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia. | ||||||||||||||||||||
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D-5-Hydroxytryptophan | D-5-Hydroxytryptophan (D-5-HTP) is the D-isomer of 5-HTP and can be isolated from DL-5-hydroxytryptophan by continuous separation. Compared with intraperitoneal administration of L-5-Hydroxytryptophan, which can induce dose-dependent backward walking behavior in mice, D-5-Hydroxytryptophan has no significant effect on mouse behavior and is a negative control. D-5-Hydroxytryptophan is also a 5-HT ligand, capable of binding to the 5-HT site with affinity in the micromolar range. | |||||||||||||||||||||
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6-Chloro-L-tryptophan | 99.50% | 6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ. | ||||||||||||||||||||
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5-Bromo-DL-tryptophan | 98.48% | 5-Bromo-DL-tryptophan is a natural product which can be obtained from Aspergillus fumigatus. | ||||||||||||||||||||
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6-Methyl-DL-tryptophan | 99.22% | 6-Methyl-DL-tryptophan is a kind of biochemical reagent. | ||||||||||||||||||||
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References
- [1]. Gartside SE, et al. Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors. Eur J Pharmacol. 1990 Apr 10;179(1-2):103-9. [Content Brief]
- [2]. Gijsman HJ, et al. Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers. J Clin Psychopharmacol. 2002 Apr;22(2):183-9. [Content Brief]
- [3]. Schruers K, et al. Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients. Psychiatry Res. 2002 Dec 30;113(3):237-43. [Content Brief]
