18525-25-2
18525-25-2
Chemical Structure
Serotonin maleate
Synonym(s): 5-Hydroxytryptamine maleate; 5-HT maleate
- CAS No.: 18525-25-2
- Formula:C14H16N2O5
- Molecular Weight:292.29
InChIKey: LTEXAUVYLLADEB-BTJKTKAUSA-N
SMILES: NCCC(C1=C2)=CNC1=CC=C2O.OC(/C=C\C(O)=O)=O
Biological Activity: Serotonin hydrogen maleate is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrogen maleate is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM [1] [2].
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Serotonin maleate | Serotonin hydrogen maleate is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrogen maleate is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM . | |||||||||||||||||||||
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References
- [1]. Tsao D, et al. Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity. Mol Pain. 2012 Apr 13;8:25. [Content Brief]
- [2]. Shajib MS, et al. Interleukin 13 and serotonin: linking the immune and endocrine systems in murine models of intestinal inflammation. PLoS One. 2013 Aug 28;8(8):e72774. [Content Brief]
Keywords
