Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
118 Results for "
M.tuberculosis
" in MedChemExpress (MCE) Product Catalog:
Products (118)
118 Results for "M.tuberculosis" in MCE Product Catalog:
Cat. No.: HY-B0271S1
Synonyms: Pyrazinecarboxamide-13C,15N; Pyrazinoic acid amide-13C,15N
Cat. No.: HY-N11048
CAS No.: 2209112-96-7
Target:
Category:
Cat. No.: HY-109587B
CAS No.: 2703867-74-5
BM635 mesylate is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 mesylate has a MIC50 of 0.6 μM against M. tuberculosis H37Rv. BM635 mesylate significantly improves the bioavailability compared to free-base BM635 .
Cat. No.: HY-146104
CAS No.: 2409926-02-7
Antimycobacterial agent-1 (compound 33) has selectively antimycobacterial activity against Mycobacterium tuberculosis (M. tuberculosis) H37Ra with a MIC value of 1 μg/ml. Antimycobacterial agent-1 has relatively low cytotoxicity in normal cells (Vero cells IC50 = 143.2 μg/ml) .
Cat. No.: HY-136348
CAS No.: 1630160-25-6
ML338 is a selective small molecule inhibitor probe of non-replicating Mycobacterium tuberculosis bacilli and is against the non-replicating M. tuberculosis with IC90 and IC99 values of 1 μM and 4 μM, respectively by CFU. ML338 is a invaluable tool for identifying both essential functions and vulnerabilities of the M. tuberculosis bacilli in the nutrient deprivation states. ML338 can be used for the study of M. tuberculosis chemotherapy .
Cat. No.: HY-146699
CAS No.: 2987763-18-6
Target:
Research Areas:
MtTMPK-IN-5 (compound 17) is a potent M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC50 value of 34 μM. MtTMPK-IN-5 combines favorable enzyme inhibitory activity with significant activity against M. tuberculosis (MIC = 12.5 μM). MtTMPK-IN-5 can be used for researching tuberculosis .
Cat. No.: HY-14990A
CAS No.: 1044503-04-9
Synonyms: LL 3858 hydrochloride
Sudoterb (LL 3858) hydrochloride is an orally active anti-Tuberculosis agent .
Cat. No.: HY-146555
CAS No.: 2408627-49-4
Antitubercular agent-14 (Compound 1) is an antitubercular agent with an MIC of 0.3 µg/mL against M. tuberculosis .
Cat. No.: HY-E70360A
Acid phosphatase, M. tuberculosis (EC 3.1.3.2) is one of the main enzymes of Mycobacterium tuberculosis metabolism. Acid phosphatase, M. tuberculosis (EC 3.1.3.2) is a probable target for antituberculosis compounds.
Cat. No.: HY-100725R
CAS No.: 146204-42-4
Target:
Research Areas:
BM212 (Standard) is the analytical standard of BM212. This product is intended for research and analytical applications. BM212 is a potent Mycobacterial membrane protein Large 3 (MmpL3) inhibitor. BM212 has strong bactericidal activity against both M. tuberculosis and some nontuberculosis mycobacteria. BM212 exhibits antimycobacterial activity against M. tuberculosis H37Rv with an MIC of 5 µM .
Cat. No.: HY-146055
CAS No.: 2411740-98-0
Antituberculosis agent-1 (Compound 8a) is an antituberculosis agent with an MIC of 3.84 μg/mL against M. tuberculosis H37Rv .
Cat. No.: HY-156414
Target:
Research Areas:
DHFR-IN-11 (compound 6b) is inhibitor of DHFR, and has inhibitory potency versus M. tuberculosis DHFR enzyme with IC50 values 5.70 μM .
Cat. No.: HY-N12600
CAS No.: 3034042-33-3
Target:
Cat. No.: HY-146700
CAS No.: 2225885-99-2
Target:
Research Areas:
MtTMPK-IN-6 (compound 1) is a potent M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC50 value of 29 μM. MtTMPK-IN-6 can be used for researching tuberculosis .
Cat. No.: HY-139596
CAS No.: 2221801-50-7
Target:
Research Areas:
Polyketide synthase 13-IN-3 (compound 41) is a polyketide synthase 13 inhibitor，with a MIC of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv .
Cat. No.: HY-156412
CAS No.: 929484-47-9
DHFR-IN-10 (compound 4c) is a potent DHFR inhibitor, with an IC50 of 4.21 μM for M. tuberculosis DHFR enzyme. DHFR-IN-10 exhibits potent antituberculosis efficiency .
Cat. No.: HY-146119
CAS No.: 1845719-43-8
Antitubercular agent-24 (Compound 1) is an anti-tubercular agent with an extracellular IC50 of 0.83 μM and an intracellular IC50 of 0.17 μM against M. tuberculosis H37Rv .
Cat. No.: HY-147661
CAS No.: 331942-46-2
Target:
Research Areas:
DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor for MtDHFR (dihydrofolate reductase from M. tuberculosis), with an IC50 of 7 μM. DHFR-IN-2 can be used for tuberculosis (TB) research .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
