DHFR-IN-11
DHFR-IN-11 (compound 6b) is inhibitor of DHFR, and has inhibitory potency versus M. tuberculosis DHFR enzyme with IC50 values 5.70 μM.
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- Formule: C18H17N3O3S2
- Masse moléculaire:387.48
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
5.70 μM versus M. tuberculosis DHFR enzyme[1].
Chemical Information
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Masse moléculaire 387.48
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Formule C18H17N3O3S2
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SMILES
O=C1N=C(N2N=C(C3=CC=CS3)CC2C4=CC(OC)=CC=C4OC)SC1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Dawood DH, et, al. New Thiophenyl-pyrazolyl-thiazole Hybrids as DHFR Inhibitors: Design, Synthesis, Antimicrobial Evaluation, Molecular Modeling, and Biodistribution Studies. ACS Omega. 2023 Oct 13;8(42):39250-39268. [Content Brief]
[2]. Dawood DH, et al. New Thiophenyl-pyrazolyl-thiazole Hybrids as DHFR Inhibitors: Design, Synthesis, Antimicrobial Evaluation, Molecular Modeling, and Biodistribution Studies. ACS Omega. 2023;8(42):39250-39268. Published 2023 Oct 13. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DHFR-IN-11 Related Classifications
HY-156414 Related Classifications
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