46 Results for "

SHP1

" in MedChemExpress (MCE) Product Catalog:
Products (46)

46 Results for "SHP1" in MCE Product Catalog:

Cat. No.: HY-P992434

Research Areas:  

Cancer

OSE-279 is a high-affinity humanized monoclonal bivalent antibody targeting PD-1, the recommended isotype control is HY-P99003. OSE-279 blocks PD-1 ligand binding, inhibits PDL1-induced SHP1 phosphorylation, restores T cell activation, and promotes reactivation of primary T cell effector functions. OSE-279 binds hFcRn receptor, predicts long half-life, induces CD4 and CD8 T cell proliferation, and promotes interleukin 2 and interferon gamma secretion. OSE-279 can be used for the research of advanced malignancies, colon cancer, hepatocarcinoma, mesothelioma [1] .
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Cat. No.: HY-RS21668
Research Areas:  

Others

Nr0b2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nr0b2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23761
Research Areas:  

Others

Ptpn6 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptpn6 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17207
Research Areas:  

Others

Sirpa Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sirpa gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17306
Research Areas:  

Others

Ptpn6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptpn6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-W283930
CAS No.: 132858-26-5
YHV98-4 is a selective, blood-brain barrier-permeable Hv1 inhibitor with an IC50 of 0.7 μM. YHV98-4 reduces ROS production and restores the SHP-1-pAKT signaling pathway. YHV98-4 decreases the spread of hyperphosphorylated Tau protein. YHV98-4 alleviates inflammation and produces analgesic effects. YHV98-4 improves cognitive function in mouse models of Alzheimer's disease. YHV98-4 can be used in research related to inflammatory pain, neuropathic pain and Alzheimer's disease [1] .
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