57 Results for "

TIM-3

" in MedChemExpress (MCE) Product Catalog:
Products (57)

57 Results for "TIM-3" in MCE Product Catalog:

Cat. No.: HY-P992342

Target:  

Tim3

Research Areas:  

Cancer

DCB-8 is a specific inhibitor targeting human TIM-3. DCB-8 regulates T cell function, enhances cytokine secretion, and inhibits tumor growth in disease animal models. DCB-8 can be used for cancer research .
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Cat. No.: HY-P992454

Target:  

Tim3

Research Areas:  

Cancer

S095018 (Sym023) is a human IgG2-type inhibitor targeting T cell immunoglobulin and TIM-3. S095018 competitively blocks the binding of multiple ligands such as Gal-9 and phosphatidylserine to TIM-3. S095018 stimulates the anti-tumor activity of T cells, dendritic cells and macrophages, and exhibits good safety both as a monotherapy and in combination with the anti-PD-1 antibody Sym021. S095018 also induces an increase in the density of CD8 + T cells in the tumor microenvironment, and upregulates gene signatures associated with IFN-γ signaling, antigen presentation and T cell activation. S095018 can be used for the research of advanced/metastatic recurrent biliary tract cancer .
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Cat. No.: HY-P7415
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HAVCR2; FLJ14428; Hepatitis A Virus Cellular Receptor 2; HAVcr-2; TIMD3; TIMD-3; TIM3; T-Cell Immunoglobulin And Mucin Domain 3; TIM-3; T Cell Immunoglobulin Mucin 3; CD366; Kidney Injury Molecule-3; T-Cell Immunoglobulin And Mucin Domain-Containing Prote
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-RS17115
Research Areas:  

Others

Havcr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Havcr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P8F041A
Synonyms: CD366(TIM-3),CD366-FITC,F38-2E2

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F041C
Synonyms: CD366(TIM-3),CD366-PE,F38-2E2

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F041F
Synonyms: CD366(TIM-3),CD366-PerCP,F38-2E2

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F041I
Synonyms: CD366(TIM-3),CD366-APC,F38-2E2

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F041B
Synonyms: CD366(TIM-3),CD366-AF488,F38-2E2

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F041H
Synonyms: CD366(TIM-3),CD366-AF647,F38-2E2

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F041K
Synonyms: CD366(TIM-3),CD366-AF700,F38-2E2

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F041L
Synonyms: CD366(TIM-3),CD366-PC Blue,F38-2E2

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F041D
Synonyms: CD366(TIM-3),CD366-PE-Cy7,F38-2E2

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F041E
Synonyms: CD366(TIM-3),CD366-PE-CF596,F38-2E2

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F041J
Synonyms: CD366(TIM-3),CD366-APC-Cy7,F38-2E2

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F041G
Synonyms: CD366(TIM-3),CD366-PerCP-Cy5.5,F38-2E2

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P992366

Target:  

Galectin Tim3

Research Areas:  

Cancer

HFB200901 is a galectin LGALS9 inhibitor and immunostimulant that can be used in studies related to pancreatic adenocarcinoma, pancreatic intraepithelial neoplasia, KRAS G12C-mutant colon cancer, and prostate cancer. HFB200901 disrupts the LGALS9/TIM-3 axis, while blocking the internalization and vacuolization of recombinant LGALS9. HFB200901 reduces the proportion of regulatory T cells (Treg) and enhances dendritic cell activation, thereby inducing polyfunctional and memory CD8 + T cell responses. HFB200901 inhibits the progression of pancreatic neoplastic lesions and effectively improves the efficacy of PSMA-based vaccination [3] .
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