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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
443 Results for "
factor D
" in MedChemExpress (MCE) Product Catalog:
Products (443)
443 Results for "factor D" in MCE Product Catalog:
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FD-IN-1 (Compound 12) is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5 µM, respectively .
Cat. No.: HY-P990952
CAS No.: 2527079-60-1
Synonyms: OMS906
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Factor D inhibitor 6 is a potent, highly selective and orally active factor D (FD) inhibitor with an IC50 of 30 nM and a Kd of 6 nM. Factor D inhibitor 6 is inactive against factor B, lassical and lectin complement-pathway activation, and a broad assay panel of receptors, ion channels, kinases and proteases .
Synonyms: D21-2393
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Edoxaban M4 (D21-2393) is an orally active and selective Factor Xa inhibitor with a human Factor Xa IC50 of 1.8 nM. Edoxaban M4 exhibits anticoagulant activity via Factor Xa inhibition. Edoxaban M4 can be used for the research of non-valvular atrial fibrillation, venous thromboembolisms, pulmonary embolism .
Cat. No.: HY-W019721
CAS No.: 63775-96-2
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c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, an kinase inhibitor of FMS (Colony stimulating factor-1 receptor, CSF-1R) with IC50 of 2 nM.
c-Fms-IN-10 has anti-tumor activity .
Cat. No.: HY-N5037
CAS No.: 109008-27-7
Category:
Cardiovascular Disease Aquifoliaceae Triterpenes Terpenoids Plants Disease Research Fields Tabernaemontana elegans Stapf
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CH3OCO-D-CHA-Gly-Arg-pNA acetate is a chromogenic substrate for factor Xa .
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Cholesterol β-D-glucoside (Cholesteryl glucoside) is a heat shock transcription factor 1 (HSF1) activator. Cholesterol β-D-glucoside induces HSP70 in fibroblast cells .
Cat. No.: HY-W012572
CAS No.: 351-50-8
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D-Histidine is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu 2+) .
Cat. No.: HY-50875
CAS No.: 217099-44-0
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BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.
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Complement factor D-IN-1 is a potent and selective small-molecule reversible factor d inhibitor, with IC50s of 0.006 and 0.05 μM in FD Thioesterolytic Fluorescent Assay and a MAC Deposition Assay, respectively.
Cat. No.: HY-N8102
CAS No.: 99633-30-4
Category:
Cardiovascular Disease Triterpenes other families Terpenoids Plants Disease Research Fields
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Cat. No.: HY-P99298
CAS No.: 1278466-20-8
Synonyms: RG 7417; TNX 234; Anti-CFD Recombinant Antibody
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Cat. No.: HY-P99875
CAS No.: 2252477-42-0
Synonyms: BIVV-001; Altuvoct
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Cat. No.: HY-P6023
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Synonyms: asandeutertinibum; Osimertinib-d3; AZD-9291-d3
Cat. No.: HY-W011690S
CAS No.: 182755-41-5
Cat. No.: HY-B0511S2
CAS No.: 2985952-90-5
Synonyms: Vitamin B7-d2; Vitamin H-d2; D-Biotin-d2
Cat. No.: HY-B0511S
CAS No.: 1217481-41-8
Synonyms: Vitamin B7 d2-1; Vitamin H d2-1; D-Biotin d2-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
