443 Results for "

factor D

" in MedChemExpress (MCE) Product Catalog:
Products (443)

443 Results for "factor D" in MCE Product Catalog:

Cat. No.: HY-N2370R
CAS No.: 30271-38-6
24-Hydroxycholesterol is a natural sterol, which serves as a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR, and a potent activator of the transcription factors LXR.
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Cat. No.: HY-50874
CAS No.: 217099-43-9
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

BCX 1470 inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.
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Cat. No.: HY-141570S
CAS No.: 201216-37-7
Purity:  ≥99.0%
Synonyms: Lyso-platelet-activating factor C-16-d4
Lyso-PAF C-16-d4 (Lyso-platelet-activating factor C-16-d4) is the deuterated-labeled Lyso-PAF C-16 (HY-141570). Lyso-PAF C-16 is a precursor and metabolite of 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (PAF C-16). Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway or selective acylation with arachidonic acid by a CoA-independent transacylase .
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Cat. No.: HY-138281
CAS No.: 1903742-34-6
Purity:  99.33%
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. Complement factor D-IN-2 can be used for the research of autoimmune diseases .
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Cat. No.: HY-10268S
CAS No.: 2098655-51-5
Purity:  99.02%
Synonyms: PRT054021-d6
Betrixaban-d6 is a deuterium labeled Betrixaban. Betrixaban is a highly potent, selective, and orally efficacious factor Xa (fXa) inhibitor .
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Cat. No.: HY-B0511S1
CAS No.: 1217850-77-5
Synonyms: rel-Vitamin B7-d4; rel-Vitamin H-d4; rel-D-Biotin-d4
rel-Biotin-d4 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
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Cat. No.: HY-N15385
CAS No.: 137592-04-2
Hericenone D, an orally active pancreatic lipase inhibitor, can be found in Hericium erinaceus. Hericenone D reduces lipid absorption and stimulates nerve growth factor NGF gene expression. Hericenone D can be used for the research of menopausal obesity .
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Cat. No.: HY-N3938
CAS No.: 110414-77-2
Gelsemiol is the main active ingredient in Verbena littoralis H. B. K.. Gelsemiol enhanced nerve growth factor (NGF) -induced axonal elongation in PC12D cells .
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Cat. No.: HY-W012572A
CAS No.: 328526-86-9
D-Histidine hydrochloride hydrate is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine hydrochloride hydrate works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine hydrochloride hydrate downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine hydrochloride hydrate is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu 2+) .
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Cat. No.: HY-177123
CAS No.: 2922808-66-8
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Refinicopan is a complement factor D inhibitor with an IC50 of 10 nM. Refinicopan inhibits hemolysis of rabbit red blood cells. Refinicopan can be used to study diseases mediated by complement factor D .
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Cat. No.: HY-172239
CAS No.: 2378381-06-5
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Tarvicopan is an inhibitor for complement factor D .
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Cat. No.: HY-B0239S2
Threo-Chloramphenicol-d6 is the deuterium labeled Chloramphenicol . Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .
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Cat. No.: HY-N8218
CAS No.: 14982-11-7
Homoeriodictyol 7-O-β-D-glucoside is a natural platelet-activating factor (PAF) antagonist. Homoeriodictyol 7-O-β-D-glucoside inhibits human and rabbit platelet aggregation induced by PAF, with an IC50 of 0.8 μM .
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Cat. No.: HY-18970
CAS No.: 1164464-14-5
Research Areas:  

Inflammation/Immunology

TG6-129 is a selective antagonist of the EP2 receptor. TG6-129 reduces the expression of inflammatory factors induced by butaprost in P388D1 macrophages .
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Cat. No.: HY-101731
CAS No.: 167011-22-5
Target:  

Leukotriene Receptor

Research Areas:  

Inflammation/Immunology

CP-96021 hydrochloride is a balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonist with Ki values of 34 nM and 37 nM, respectively .
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Cat. No.: HY-P4750
CAS No.: 93942-91-7
Target:  

GHSR

Research Areas:  

Endocrinology

Acetyl-(D-Arg2)-GRF (1-29) amide (human) is an antagonist of growth hormone releasing factor (GRF). Acetyl-(D-Arg2)-GRF (1-29) amide (human) inhibits the release of growth hormone (GH) and can be used for endocrine research .
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Cat. No.: HY-10984S
CAS No.: 1377838-49-7
Synonyms: CC-4047-d5
Pomalidomide-d5 is deuterium labeled Pomalidomide. Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors.
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Cat. No.: HY-P2830
CAS No.: 37213-56-2
Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

Complement factor D is a serine protease. Complement factor D activates C3 convertase by specifically cleaving complement Factor B. Complement factor D is promising for research of autoimmune diseases (e.g., paroxysmal nocturnal hemoglobinuria, C3 glomerulopathy), age-related macular degeneration, and thrombotic microangiopathies .
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Cat. No.: HY-P10658
CAS No.: 143228-35-7
Target:  

Phospholipase

Research Areas:  

Others

ARF1 (2-17) inhibits both ARF-independent (PLC-β) and ARF-dependent (PLD) pathways. ARF1 (2-17) inhibits GTP-γ-S-stimulated PLD activity, phospholipase C-β (PLC-β), and exocytosis .
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Cat. No.: HY-15494S1
Synonyms: AXL1717-d6; Picropodophyllotoxin-d6; PPP-d6
Picropodophyllin-d6 (AXL1717-d6) is deuterium labeled Picropodophyllin. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.
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