Complement factor D-IN-2
Based on 1 Customer Validation
Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. Complement factor D-IN-2 can be used for the research of autoimmune diseases.
For research use only. We do not sell to patients.
- Purity: 99.33%
- CAS No.: 1903742-34-6
- Formula: C27H24BrN7O3
- Molecular Weight:574.43
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
complement factor D[1]
Chemical Information
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CAS No. 1903742-34-6
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Appearance Solid
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Molecular Weight 574.43
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Formula C27H24BrN7O3
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Color White to off-white
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SMILES
O=C([C@H]1N(C(CN2N=C(C(C)=O)C3=C2C=CC(C4=CN=C(C)N=C4)=C3)=O)[C@]5([H])C[C@]5([H])C1)NC6=NC(Br)=CC=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (174.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7409 mL | 8.7043 mL | 17.4086 mL | 43.5214 mL |
| 5 mM | 0.3482 mL | 1.7409 mL | 3.4817 mL | 8.7043 mL | |
| 10 mM | 0.1741 mL | 0.8704 mL | 1.7409 mL | 4.3521 mL | |
| 15 mM | 0.1161 mL | 0.5803 mL | 1.1606 mL | 2.9014 mL | |
| 20 mM | 0.0870 mL | 0.4352 mL | 0.8704 mL | 2.1761 mL | |
| 25 mM | 0.0696 mL | 0.3482 mL | 0.6963 mL | 1.7409 mL | |
| 30 mM | 0.0580 mL | 0.2901 mL | 0.5803 mL | 1.4507 mL | |
| 40 mM | 0.0435 mL | 0.2176 mL | 0.4352 mL | 1.0880 mL | |
| 50 mM | 0.0348 mL | 0.1741 mL | 0.3482 mL | 0.8704 mL | |
| 60 mM | 0.0290 mL | 0.1451 mL | 0.2901 mL | 0.7254 mL | |
| 80 mM | 0.0218 mL | 0.1088 mL | 0.2176 mL | 0.5440 mL | |
| 100 mM | 0.0174 mL | 0.0870 mL | 0.1741 mL | 0.4352 mL |
Complement factor D-IN-2 Related Classifications
HY-138281 Related Classifications
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