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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
166 Results for "
fms
" in MedChemExpress (MCE) Product Catalog:
Products (166)
166 Results for "fms" in MCE Product Catalog:
Cat. No.: HY-161706
CAS No.: 3047930-25-3
c-Fms-IN-15 (compound 8g) is a potent inhibitor of FMS kinase, with the IC50 of 563 nM .
Cat. No.: HY-118768
CAS No.: 302556-51-0
Target:
Research Areas:
FMS586 free base is a selective neuropeptide Y Y5 receptor antagonist with oral activity. FMS586 can completely block the significant increase in adrenocorticotropic hormone (ACTH) and cortisol caused by the Y(5) selective agonist hPP. FMS586 also reversed the significant upregulation of adrenocorticotropic hormone (CRF) and antidiuretic hormone (AVP) mRNA expression induced by central injection of hPP. FMS586 provides the first evidence that selective stimulation of Y(5) receptors triggers activation of the HPA axis .
Cat. No.: HY-13838A
CAS No.: 1779796-38-1
Research Areas:
PLX647 dihydrochloride is an orally active, highly specific dual FMS and KIT kinase inhibitor, with IC50s of 28 and 16 nM, reapectively. PLX647 dihydrochloride shows selectivity for FMS and KIT over a panel of 400 kinases at a concentration of 1 μM except FLT3 and KDR (IC50s=91 and 130 nM, respectively) .
Cat. No.: HY-RS03229
Target:
Research Areas:
Csf1r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Csf1r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03228
Target:
Research Areas:
CSF1R Human Pre-designed siRNA Set A contains three designed siRNAs for CSF1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-174684
Human FLT1 mRNA encodes the human fms related receptor tyrosine kinase 1 (FLT1) protein, a member of the vascular endothelial growth factor receptor (VEGFR) family. FLT1 binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis.
Cat. No.: HY-W011873R
CAS No.: 373-49-9
Synonyms: GW786034-13C,d3 hydrochloride
Cat. No.: HY-108263S
Synonyms: CGP52421-d5
Cat. No.: HY-10208S1
CAS No.: 1261734-88-6
Synonyms: GW786034-13C,d3
Cat. No.: HY-10917R
CAS No.: 870483-87-7
Target:
Research Areas:
GW2580 (Standard) is the analytical standard of GW2580. This product is intended for research and analytical applications. GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 μM. GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling .
Cat. No.: HY-13839
CAS No.: 923562-22-5
PLX647-OMe is a 5-methoxy analog of PLX647 (HY-13838) and a FMS (CSF1R) inhibitor derived from a 7-azaindole scaffold with an IC50 of 62 nM. PLX647-OMe can be used in research related to FMS-mediated diseases, such as cancer .
Cat. No.: HY-P72955A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. fms; Macrophage Colony Stimulating Factor I Receptor; C-fms; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; fms Proto-Oncogene; McDonough Feline Sarcoma Viral (V-fms) Oncogene Homolog; BANDDOS; Macr
Species:
Rat
Source:
HEK293
Cat. No.: HY-P78637
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. fms; Macrophage Colony Stimulating Factor I Receptor; C-fms; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; fms Proto-Oncogene; McDonough Feline Sarcoma Viral (V-fms) Oncogene Homolog; BANDDOS; Macr
Species:
Canine
Source:
HEK293
Cat. No.: HY-P78892
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. fms; Macrophage Colony Stimulating Factor I Receptor; C-fms; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; fms Proto-Oncogene; McDonough Feline Sarcoma Viral (V-fms) Oncogene Homolog; BANDDOS; Macr
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P70124
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. fms; Macrophage Colony Stimulating Factor I Receptor; C-fms; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; fms Proto-Oncogene; McDonough Feline Sarcoma Viral (V-fms) Oncogene Homolog; BANDDOS; Macr
Species:
Cynomolgus
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
