167 Results for "

intercalator

" in MedChemExpress (MCE) Product Catalog:
Products (167)

167 Results for "intercalator" in MCE Product Catalog:

Cat. No.: HY-19829
CAS No.: 100940-65-6
Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity .
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Cat. No.: HY-U00337
CAS No.: 105118-14-7
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities.
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Cat. No.: HY-D1102
CAS No.: 864281-70-9
DNA intercalator 3 is a DNA intercalating agent that can be used for DNA staining.
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Cat. No.: HY-101541S
CAS No.: 2687960-96-7
Synonyms: Methyl docosahexaenoate-d5; all cis-DHA methyl ester-d5
Docosahexaenoic acid-d5 methyl ester is the deuterium labeled Docosahexaenoic Acid methyl ester. Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog which can be intercalated into membrane phospholipids without being oxidized or hydrolyzed .
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Cat. No.: HY-114325
CAS No.: 2411007-69-5
Research Areas:  

Cancer

AcLysValCit-PABC-DMAE-SW-163D is a agent-linker conjugates for ADC which consists of a natural bis-intercalator, SW-163D, conjugated via an AcLysValCitPABC-DMAE linker .
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Cat. No.: HY-D1095
CAS No.: 1268616-88-1
Cy7 DiAcid belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
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Cat. No.: HY-105293
CAS No.: 910229-23-1
Research Areas:  

Cancer

NSC 727357 is a DNA intercalator and topoisomerase inhibitor with antitumor activity. NSC 727357 can inhibit cells proliferation and induce G1 phase arrest. NSC 727357 can be used for the research of cancer, such as melanoma .
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Cat. No.: HY-13727B
CAS No.: 175989-38-5
Synonyms: BBR 2778 hydrochloride
Target:  

Topoisomerase

Research Areas:  

Cancer

Pixantrone (BBR 2778 (free base)) hydrochloride, a mitoxantrone analog, is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity .
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Cat. No.: HY-W016840
CAS No.: 14510-06-6
8-Hydroxyquinoline-2-carbaldehyde is a quinoline derivative with the functions of DNA intercalation, hydroxyl radical scavenging and superoxide radical scavenging. 8-Hydroxyquinoline-2-carbaldehyde serves as a precursor for synthesizing Schiff base ligands with DNA intercalation activity and antioxidant properties. 8-Hydroxyquinoline-2-carbaldehyde can be used in relevant research across multiple fields including materials science and biomedicine .
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Cat. No.: HY-D1246
CAS No.: 58880-05-0
Ethidium monoazide bromide is a DNA intercalating fluorescent dye that enters bacteria with damaged membranes. Ethidium monoazide bromide can be covalently linked to DNA by photoactivation. Ethidium monoazide bromide stains only dead cells . Ethidium monoazide (bromide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-124122
CAS No.: 1802665-43-5
BPTQ is a potent inhibitor against VEGFR1 and CHK2 with IC50 values of 0.54 and 1.70 µmol/L, respectively. BPTQ is also an intercalator of DNA with anticancer activities. BPTQ inhibits the proliferation of HL-60 cells by arresting cells at S and G2/M phase with an IC50 value of 12 µmol/L. BPTQ also activates the mitochondria-mediated Apoptosis pathway by a decrease in mitochondrial membrane potential, increase in the Bax:Bcl-2 ratio and activation of caspases .
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Cat. No.: HY-D1100
CAS No.: 864281-61-8
DNA intercalator 1 is a DNA intercalating agent that can be used for DNA staining.
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Cat. No.: HY-D1101
CAS No.: 864281-69-6
DNA intercalator 2 is a DNA intercalating agent that can be used for DNA staining.
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Cat. No.: HY-121649
CAS No.: 70476-63-0
Target:  

Topoisomerase

Research Areas:  

Cancer

AQ4 is a topoisomerase II inhibitor and DNA intercalator as a chemically stable cytotoxic agent in many human tumor lines .
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Cat. No.: HY-D1326
CAS No.: 1361402-15-4
Cyanine3 carboxylic acid belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
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Cat. No.: HY-B1741A
CAS No.: 531-73-7
Research Areas:  

Infection Cancer

3,6-Diaminoacridine dihydrochloride is a versatile acridine compound. 3,6-Diaminoacridine dihydrochloride exerts antibacterial activity by intercalating into bacterial DNA, interfering with replication and transcription, and inducing bacterial lysis. 3,6-Diaminoacridine dihydrochloride is an acridine dye and also a DNA intercalator .
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Cat. No.: HY-13727AR
CAS No.: 144675-97-8
Synonyms: BBR 2778 (Standard)
Research Areas:  

Cancer

Pixantrone (Standard) is the analytical standard of Pixantrone. This product is intended for research and analytical applications. Pixantrone (BBR 2778) dimaleate is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity.
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Cat. No.: HY-162381
Target:  

Topoisomerase

Research Areas:  

Cancer

Topoisomerase II inhibitor 19 (compound 5h) is a DNA intercalator and topoisomerase II inhibitor (IC50 value of 0.34 μM). Topoisomerase II inhibitor 19 would induce detectable potent damage in ctDNA .
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Cat. No.: HY-146063
CAS No.: 2933882-99-4
Target:  

Apoptosis

Research Areas:  

Cancer

Anticancer agent 54 is a potent anticancer agent. Anticancer agent 54 shows antiproliferative activity. Anticancer agent 54 induces apoptosis and cell cycle arrest at G0/G1 phases. Anticancer agent 54 shows anticancer activity depends on DNA intercalation and ROS generation .
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Cat. No.: HY-100875R
CAS No.: 78186-34-2
Synonyms: CL216942 (Standard)
Research Areas:  

Cancer

Bisantrene (Standard) is the analytical standard of Bisantrene. This product is intended for research and analytical applications. Bisantrene is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation. Bisantrene targets eukaryotic type II topoisomerases. Bisantrene is a substrate of MDR1 .
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