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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
167 Results for "
intercalation
" in MedChemExpress (MCE) Product Catalog:
Products (167)
167 Results for "intercalation" in MCE Product Catalog:
Referencia número: HY-19829
No. CAS: 100940-65-6
Category:
Infection Microorganisms Antibiotics Disease Research Antibacterial Anticancer Disease Research Fields Other Antibiotics
Target:
Referencia número: HY-U00337
No. CAS: 105118-14-7
Target:
Áreas de investigación:
Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities.
Referencia número: HY-101541S
No. CAS: 2687960-96-7
Synonyms: Methyl docosahexaenoate-d5; all cis-DHA methyl ester-d5
Referencia número: HY-114325
No. CAS: 2411007-69-5
Target:
Áreas de investigación:
AcLysValCit-PABC-DMAE-SW-163D is a agent-linker conjugates for ADC which consists of a natural bis-intercalator, SW-163D, conjugated via an AcLysValCitPABC-DMAE linker .
Referencia número: HY-D1095
No. CAS: 1268616-88-1
Referencia número: HY-105293
No. CAS: 910229-23-1
Target:
Áreas de investigación:
NSC 727357 is a DNA intercalator and topoisomerase inhibitor with antitumor activity. NSC 727357 can inhibit cells proliferation and induce G1 phase arrest. NSC 727357 can be used for the research of cancer, such as melanoma .
Referencia número: HY-13727B
No. CAS: 175989-38-5
Synonyms: BBR 2778 hydrochloride
Target:
Áreas de investigación:
Pixantrone (BBR 2778 (free base)) hydrochloride, a mitoxantrone analog, is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity .
Referencia número: HY-W016840
No. CAS: 14510-06-6
Referencia número: HY-D1246
No. CAS: 58880-05-0
Referencia número: HY-124122
No. CAS: 1802665-43-5
Áreas de investigación:
BPTQ is a potent inhibitor against VEGFR1 and CHK2 with IC50 values of 0.54 and 1.70 µmol/L, respectively. BPTQ is also an intercalator of DNA with anticancer activities. BPTQ inhibits the proliferation of HL-60 cells by arresting cells at S and G2/M phase with an IC50 value of 12 µmol/L. BPTQ also activates the mitochondria-mediated Apoptosis pathway by a decrease in mitochondrial membrane potential, increase in the Bax:Bcl-2 ratio and activation of caspases .
Referencia número: HY-D1102
No. CAS: 864281-70-9
Referencia número: HY-121649
No. CAS: 70476-63-0
Target:
Áreas de investigación:
AQ4 is a topoisomerase II inhibitor and DNA intercalator as a chemically stable cytotoxic agent in many human tumor lines .
Referencia número: HY-D1326
No. CAS: 1361402-15-4
3,6-Diaminoacridine dihydrochloride is a versatile acridine compound. 3,6-Diaminoacridine dihydrochloride exerts antibacterial activity by intercalating into bacterial DNA, interfering with replication and transcription, and inducing bacterial lysis. 3,6-Diaminoacridine dihydrochloride is an acridine dye and also a DNA intercalator .
Referencia número: HY-13727AR
No. CAS: 144675-97-8
Synonyms: BBR 2778 (Standard)
Target:
Áreas de investigación:
Pixantrone (Standard) is the analytical standard of Pixantrone. This product is intended for research and analytical applications. Pixantrone (BBR 2778) dimaleate is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity.
Referencia número: HY-162381
Target:
Áreas de investigación:
Topoisomerase II inhibitor 19 (compound 5h) is a DNA intercalator and topoisomerase II inhibitor (IC50 value of 0.34 μM). Topoisomerase II inhibitor 19 would induce detectable potent damage in ctDNA .
Referencia número: HY-146063
No. CAS: 2933882-99-4
Anticancer agent 54 is a potent anticancer agent. Anticancer agent 54 shows antiproliferative activity. Anticancer agent 54 induces apoptosis and cell cycle arrest at G0/G1 phases. Anticancer agent 54 shows anticancer activity depends on DNA intercalation and ROS generation .
Referencia número: HY-100875R
No. CAS: 78186-34-2
Synonyms: CL216942 (Standard)
Target:
Áreas de investigación:
Bisantrene (Standard) is the analytical standard of Bisantrene. This product is intended for research and analytical applications. Bisantrene is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation. Bisantrene targets eukaryotic type II topoisomerases. Bisantrene is a substrate of MDR1 .
Referencia número: HY-130050
No. CAS: 75580-37-9
Synonyms: BBM-928 A
Category:
Target:
Referencia número: HY-D1100
No. CAS: 864281-61-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
