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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
86 Results for "
Prostatic hyperplasia
" in MedChemExpress (MCE) Product Catalog:
Products (86)
86 Results for "Prostatic hyperplasia" in MCE Product Catalog:
Cat. No.: HY-Z12431
CAS No.: 1357252-79-9
Synonyms: KMD-3293
Target:
Research Areas:
Silodosin carboxylic acid impurity (KMD-3293) is an inactive silodosin metabolite. Silodosin carboxylic acid impurity is the major metabolite that can be generated via oxidation by alcohol and aldehyde dehydrogenase. Silodosin carboxylic acid impurity can be studied in research for benign prostatic hyperplasia .
Cat. No.: HY-B0192S3
CAS No.: 1006717-31-2
Synonyms: SL 77499-d6
Cat. No.: HY-B0192S3A
CAS No.: 1006717-24-3
Synonyms: SL 77499-10-d6
Cat. No.: HY-B0661AS
Synonyms: (R)-(-)-YM12617-d5; LY253351-d5
Cat. No.: HY-B0661S
CAS No.: 1231943-97-7
Synonyms: (R)-(-)-YM12617 free base-d4; LY253351 free base-d4
Cat. No.: HY-B0661AR
CAS No.: 106463-17-6
Synonyms: (R)-(-)-YM12617 (Standard); LY253351 (Standard)
Category:
Synonyms: MK-906-d9
Cat. No.: HY-B0391S1
CAS No.: 2747918-58-5
Synonyms: KT-611-d5; BM-15275-d5
Cat. No.: HY-N13195
CAS No.: 420781-85-7
Category:
Target:
Cat. No.: HY-10122R
CAS No.: 160970-54-7
Synonyms: KAD 3213 (Standard); KMD 3213 (Standard)
Research Areas:
Silodosin (Standard) is the analytical standard of Silodosin. This product is intended for research and analytical applications. Silodosin (KAD 3213; KMD 3213) is a potent, selective and orally active α1A-adrenergic receptor (α1A-AR) blocker. Silodosin exhibits high affinity for α1A-AR (Ki=0.036 nM), over 162-fold and 50-fold than for α1B-AR and α1D-AR with Ki values of 21 nM and 2.0 nM, respectively. Silodosin is an effective and well-tolerated agent, it can be used for the investigation of LUTS/BPH .
Cat. No.: HY-162071
CAS No.: 904457-46-1
Target:
Research Areas:
PKM2-IN-5 (Compound G1) is an inhibitor for pyruvate kinase M2 (PKM2), with IC50 >70 μM .
Cat. No.: HY-B0391S2
Synonyms: KT-611-d7; BM-15275-d7
Cat. No.: HY-B0304AR
CAS No.: 129938-20-1
Synonyms: LY-210448 hydrochloride (Standard)
Research Areas:
Dapoxetine (hydrochloride) (Standard) is the analytical standard of Dapoxetine (hydrochloride). This product is intended for research and analytical applications. Dapoxetine (LY-210448) hydrochloride is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine hydrochloride can be used for the research of premature ejaculation (PE) .
Cat. No.: HY-B0304R
CAS No.: 119356-77-3
Synonyms: (S)-(+)-Dapoxetine (Standard); LY-210448 (Standard)
Research Areas:
Dapoxetine (Standard) is the analytical standard of Dapoxetine. This product is intended for research and analytical applications. Dapoxetine (LY-210448) is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine can be used for the research of premature ejaculation (PE) .
Cat. No.: HY-W753806
CAS No.: 70918-01-3
Synonyms: UK 33274 hydrochloride
Target:
Research Areas:
Doxazosin hydrochloride (UK 33274 hydrochloride) is a compound used to inhibit hypertension and prostate hyperplasia, with activity that inhibits postsynaptic α1-adrenoceptors on vascular smooth muscle. Doxazosin hydrochloride can cause vasodilation, thereby reducing peripheral vascular resistance. Doxazosin hydrochloride was found to inhibit the proliferation and migration of hepatic stellate cells in a mouse liver fibrosis model. Doxazosin hydrochloride regulates fibrosis, autophagy, and apoptosis of hepatic stellate cells by activating the PI3K/Akt/mTOR signaling pathway. Doxazosin hydrochloride also blocks autophagic flux and induces apoptosis of hepatic stellate cells .
Cat. No.: HY-183179
CAS No.: 359722-12-6
Target:
Research Areas:
α1A Adrenoceptor antagonist-1 is a selective α1A adrenoceptor antagonist with a human Ki <20 nM. α1A Adrenoceptor antagonist-1 exhibits activity against benign prostatic hyperplasia (BPH) to enable less hindered urine flow. α1A Adrenoceptor antagonist-1 relaxes α1a receptor-enriched urethral smooth muscle tissue without inducing hypotension. α1A Adrenoceptor antagonist-1 can be used for the research of benign prostatic hyperplasia (BPH) .
Cat. No.: HY-181774
CAS No.: 1807631-43-1
Target:
Research Areas:
PDE4/5-IN-1 is a selective phosphodiesterase 4/5 (PDE4/5) dual inhibitor. PDE4/5-IN-1 functionally inhibits PDE5, PDE4B2, and PDE4D2 activity. PDE4/5-IN-1 relaxes isolated rat prostate tissue, enhances nitric oxide-induced relaxation in isolated rat prostate tissue, and reduces alpha-1 adrenoceptor-mediated contractile responses in isolated rat prostate tissue. PDE4/5-IN-1 inhibits proliferation of human hyperplastic prostate cells. PDE4/5-IN-1 can be used for the research of benign prostatic hyperplasia .
Cat. No.: HY-103204R
CAS No.: 1215654-26-4
Research Areas:
RS100329 hydrochloride (Standard) is the analytical standard of RS100329 hydrochloride (HY-103204). This product is intended for research and analytical applications. RS100329 hydrochloride is a potent and selective α1A-adrenoceptor antagonist with pKi values of 9.6, 7.9 and 7.5 for α1A, α1D, and α1B, respectively. RS100329 hydrochloride inhibits reflex urethral contractions. RS100329 hydrochloride can be used in research of benign prostatic hyperplasia .
Cat. No.: HY-106391
CAS No.: 33765-68-3
Synonyms: TSAA-291
Target:
Research Areas:
Oxendolone (TSAA-291) is a steroidal antiandrogen with partial agonist properties, exhibiting a Ki value of 1.4 nM for the androgen receptor. Oxendolone exerts tissue-specific androgen receptor activity, induces unique androgen receptor conformational changes, and drives differential cofactor recruitment. Oxendolone is recruited to the androgen receptor in a PIAS1-dependent manner. Oxendolone increases levator ani muscle weight in castrated mice. Oxendolone can be used for research on benign prostatic hyperplasia .
Cat. No.: HY-N18683
CAS No.: 84604-15-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
