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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
115 Results for "
PLC
" in MedChemExpress (MCE) Product Catalog:
Products (115)
115 Results for "PLC" in MCE Product Catalog:
Cat. No.: HY-13419R
CAS No.: 112648-68-7
Research Areas:
U-73122 (Standard) is the analytical standard of U-73122 (HY-13419). This product is intended for research and analytical applications. U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC50of 1-2.1 µM for PLC.
Cat. No.: HY-184940
Target:
Research Areas:
BTK-IN-50 is a covalent BTK inhibitor with an IC50 of 6 nM. BTK-IN-50 blocks collagen-induced platelet aggregation by inhibiting the GPVI-mediated BTK-PLCγ2-PKC signaling cascade, and attenuates CRP-XL-induced phosphorylation of BTK, PLCγ2 and PKC substrates in platelets. BTK-IN-50 can be used for research related to thrombosis .
Cat. No.: HY-108630R
CAS No.: 142878-12-4
Target:
Research Areas:
U-73343 (Standard) is the analytical standard of U-73343 (HY-108630). This product is intended for research and analytical applications. U-73343, works as a protonophore, is an inactive analog of U-73122 and can be used as a negative control. U-73343 dose-dependently inhibits acid secretion irrespective of the stimulant. U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC50 of 1-2.1 μM for PLC .
Cat. No.: HY-177218
CAS No.: 500533-94-8
Synonyms: NSC 119910
Target:
Research Areas:
M119 (NSC 119910) is a Gβγ subunit and PLCβ3 inhibitor with selective activity toward μ-opioid receptor-related pathways. M119 selectively inhibits Gβγ-dependent PLCβ3 activation, reduces inositol phosphate production, and enhances μ-opioid receptor-mediated antinociception. M119 attenuates acute μ-opioid receptor agonist-induced antinociceptive tolerance and physical dependence in mice. M119 can be used for pain-related research .
Cat. No.: HY-172326
CAS No.: 1902292-78-7
Research Areas:
DPPI-4,5-P2 ammonium is a sudstrate of Phosphoinositide-specific phospholipase C-δ1 (PI-PLC-δ1) .
Cat. No.: HY-W568087
CAS No.: 212515-11-2
Target:
Research Areas:
5-Bromo-4-chloro-3-indoxyl myo-inositol-1-phosphate ammonium is a chromogenic substrate that can be used to detect the activity of phosphatidylinositol-specific phospholipase C (PI-PLC) .
Cat. No.: HY-W778574
CAS No.: 480436-84-8
Target:
Research Areas:
BAPTA tetracesium is a selective and cell-impermeant chelator for calcium. BAPTA tetracesium has high selectivity against magnesium and calcium. BAPTA tetracesium can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators .
Cat. No.: HY-P703036
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLCD4; Phospholipase C, Delta 4; Phospholipase C Delta 4; Phospholipase C-Delta-4; 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Delta-4; PLC-Delta-4; Phosphoinositide Phospholipase C-Delta-4; PLC Delta4; Phosphoinositide Phospholipase C; HPLC
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-172325
Target:
Research Areas:
DPPI-5-P (ammonium) (PtdIns-(5)-P1) can be phosphorylated to form disphosphates such as PtdIns-(4,5)-P2. DPPI-5-P (ammonium) can also be cleaved by PI-specific phospholipase C (PLC) to give inositol triphosphates .
Cat. No.: HY-111208R
CAS No.: 883098-58-6
Target:
Research Areas:
CCT129957 (Standard) is the analytical standard of CCT129957 (HY-111208). This product is intended for research and analytical applications. CCT129957 is an indole derivative and a potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of ~3 μM and a GC50 of 15 μM. CCT129957 inhibits Ca2+ release in squamous carcinoma cells at ~15 μM .
Cat. No.: HY-182335
CAS No.: 2655556-75-3
Target:
Research Areas:
PF-07245303 is a ITK/TRK inhibitor. PF-07245303 reduces the production of inflammatory cytokines such as IL-4 and IFNγ, and inhibits the phosphorylation of PLCγ1. PF-07245303 inhibits nerve growth factor-induced basophil activation and the phosphorylation of TRKA. PF-07245303 reduces oxazolone-induced ear swelling in mouse ear tissues. PF-07245303 is applicable to research related to atopic dermatitis .
Cat. No.: HY-P810555
Synonyms: PLCB3; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase beta-3; Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3
Cat. No.: HY-P991964
Synonyms: Rendomab-B49
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
