480436-84-8
480436-84-8
Chemical Structure
BAPTA tetracesium
- CAS No.: 480436-84-8
- Formula:C22H20Cs4N2O10
- Molecular Weight:1004.02
InChIKey: SLDZIKGGMGELCS-UHFFFAOYSA-J
SMILES: O=C(O[Cs])CN(CC(O[Cs])=O)C1=C(OCCOC2=C(N(CC(O[Cs])=O)CC(O[Cs])=O)C=CC=C2)C=CC=C1
Biological Activity: BAPTA tetracesium is a selective and cell-impermeant chelator for calcium. BAPTA tetracesium has high selectivity against magnesium and calcium. BAPTA tetracesium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2][3].
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BAPTA tetracesium | BAPTA tetracesium is a selective and cell-impermeant chelator for calcium. BAPTA tetracesium has high selectivity against magnesium and calcium. BAPTA tetracesium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators. | |||||||||||||||||||||
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References
- [1]. Tsien RY, et al. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 1980;19(11):2396-2404. [Content Brief]
- [2]. Hardie RC. Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid (BAPTA) and di-bromo BAPTA. Cell Calcium. 2005 Dec;38(6):547-56. [Content Brief]
- [3]. Collatz MB, et al. Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses. Cell Calcium. 1997;21(6):453-459. [Content Brief]
Keywords
