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Cat. No.: HY-108630R

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U-73343 (Standard)

U-73343 (Standard) is the analytical standard of U-73343 (HY-108630). This product is intended for research and analytical applications. U-73343, works as a protonophore, is an inactive analog of U-73122 and can be used as a negative control. U-73343 dose-dependently inhibits acid secretion irrespective of the stimulant. U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC₅₀ of 1-2.1 μM for PLC.

For research use only. We do not sell to patients.

CAS No.: 142878-12-4
Formula: C₂₉H₄₂N₂O₃
Molecular Weight:466.66

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

U-73343 (Standard) Chemical Structure

CAS No.: 142878-12-4

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 142878-12-4
Molecular Weight 466.66
Formula C₂₉H₄₂N₂O₃
SMILES

O=C(CC1)N(CCCCCCN[C@H]2CCC3C4CCC5=C(C=CC(OC)=C5)C4CC[C@]23C)C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Muto Y, et al. The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell. J Pharmacol Exp Ther. 1997 Sep;282(3):1379-88. [Content Brief]

[2]. A Tatrai, et al. U-73122, a phospholipase C antagonist, inhibits effects of endothelin-1 and parathyroid hormone on signal transduction in UMR-106 osteoblastic cells. Biochim Biophys Acta. 1994 Dec 30;1224(3):575-82. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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