176 Results for "

platelet activating factor

" in MedChemExpress (MCE) Product Catalog:
Products (176)

176 Results for "platelet activating factor" in MCE Product Catalog:

Cat. No.: HY-P5875
CAS No.: 1021346-05-3
P4pal10 is an antagonist for protease-activated receptor 4 (PAR4). P4pal10 inhibits the platelet aggregation, inhibits tissue factor (TF)-induced thrombin generation, and exhibits anticoagulant and antithrombotic activities. P4pal10 reduces the oedema and the granulocyte infiltration induced by Carrageenan (HY-125474). P4pal10 ameliorates the injury in mice myocardial ischemia/reperfusion (I/R) models .
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Cat. No.: HY-108634R
CAS No.: 105219-56-5
Synonyms: WEB 2086 (Standard)
Apafant (Standard) is the analytical standard of Apafant (HY-108634). This product is intended for research and analytical applications. Apafant (WEB 2086), a chemical probe, is a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM. Apafant increases the gene expression of PAF-r, α-globin, β-globin, decreases the c-myb gene expression. Apafant shows a protective effect on alkyl-PAF-mediated lethalit .
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Cat. No.: HY-11090
CAS No.: 209957-47-1
DPC423 free base is a selective and orally active factor Xa inhibitor with a Kis of 0.15 (human) and 0.3 (rabbit) nM. DPC423 free base exhibits Kis of 60, 61 and 6000 nM against human trypsin, plasma kallikrein and thrombin. DPC423 free base blocks the formation of prothrombinase complex, reduces thrombin production, inhibits fibrin formation and platelet activation. DPC423 free base can be used for the study of anticoagulation of arterial thrombosis .
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Cat. No.: HY-P991029
CAS No.: 2933972-64-4
Synonyms: HMB-001
Sutacimig (HMB-001) is a humanized antibody of the (H-γ4_L-κ)_(H-γ4_L-κ) format that targets FⅦa/TREML1. One arm of Sutacimig binds to endogenous FVIIa, thereby prolonging the half-life of FVIIa and increasing its accumulation in the bloodstream, while the other arm binds to TLT-1, which is exclusively expressed on the surface of activated platelets. This localizes endogenous FVIIa to activated platelets, further enhancing the activity of FVIIa. Sutacimig enhances Thrombin generation, fibrin formation, and the formation of stable fibrin-platelet networks at sites of vascular injury. Sutacimig can be used in studies related to Glanzmann thrombasthenia .
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Cat. No.: HY-P702447
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SMPD2; Lyso-PAF-PLC; Sphingomyelin Phosphodiesterase 2; N-SMase; NSMase; Sphingomyelin Phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase); Neutral Sphingomyelinase; NSMASE1; ISC1; NSMase1; Lyso-platelet-activating factor-Phospholipase C
Species:  
Human
Source:  
E. coli Cell-free
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Cat. No.: HY-P7268
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPBP; Macrophage-Derived Growth factor; Prev. THBGB1; C-X-C Motif Chemokine 7; SCYB7; Beta-Thromboglobulin; CTAP3; NAP-2-L1; CXCL7; Small Inducible Cytokine Subfamily B, Member 7; MDGF; Neutrophil-activating Peptide-2; LDGF; Low-Affinity platelet factor IV; TGB1; Neutrophil-activating Peptide 2; PBP; Small Inducible Cytokine B7; platelet Basic Protein; Small-Inducible Cytokine B7; Beta-TG; Thromboglobulin, Beta-1; CTAPIII; CXC Chemokine Ligand 7; LA-PF4; Thrombocidin 1; B-TG1; Thrombocidin 2; NAP-2; CTAP-III; TGB; THBGB; Connective Tissue-activating Peptide III; TC1; Chemokine (C-X-C Motif) Ligand 7; TC2; Pro-platelet Basic Protein; Leukocyte-Derived Growth factor
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-142669
CAS No.: 2738877-91-1
Target:  

Phospholipase

Lp-PLA2-IN-4 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-4 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 38) .
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Cat. No.: HY-142670
CAS No.: 2738877-85-3
Target:  

Phospholipase

Lp-PLA2-IN-5 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-5 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 32) .
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Cat. No.: HY-142779
CAS No.: 1620680-19-4
Target:  

Phospholipase

Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-11 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2014114249A1, compound E145) .
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Cat. No.: HY-113459
CAS No.: 745-62-0
Purity:  98.10%
Prostaglandin F1a is an endogenous metabolite and a cyclooxygenase product with platelet activity inhibitory effects. Prostaglandin F1a can be used as a marker in coagulation-related studies .
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Cat. No.: HY-P7269
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPBP; Macrophage-Derived Growth factor; Prev. THBGB1; C-X-C Motif Chemokine 7; SCYB7; Beta-Thromboglobulin; CTAP3; NAP-2-L1; CXCL7; Small Inducible Cytokine Subfamily B, Member 7; MDGF; Neutrophil-activating Peptide-2; LDGF; Low-Affinity platelet factor I
Species:  
Rat
Source:  
E. coli
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Cat. No.: HY-142778
CAS No.: 2756855-45-3
Target:  

Phospholipase

Lp-PLA2-IN-10 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-10 has the potential for the research of neurodegenerative-related diseases such as Alzheimer's disease (AD), glaucoma, age-related macular degeneration (AMD), or cardiovascular diseases including atherosclerosis (extracted from patent WO2022001881A1, compound 4) .
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Cat. No.: HY-W339834
CAS No.: 325465-92-7
Research Areas:  

Others

1-Stearoyl-sn-glycerol 3-phosphate sodium is a bioactive phospholipid that plays a crucial role in modulating cellular processes such as motility, proliferation, invasion, survival, and growth factor production, primarily through its interaction with G protein-coupled receptors (GPCRs). Typically found at low concentrations in plasma (~100nM), this compound is synthesized during the formation of membrane phospholipids and is derived from various cell types, including activated platelets, epithelial cells, leukocytes, neuronal cells, and tumor cells. Its unique structure includes stearic acid at the sn-1 position alongside a hydroxyl group at the sn-2 position.
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Cat. No.: HY-P7301
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPBP; Macrophage-Derived Growth factor; Prev. THBGB1; C-X-C Motif Chemokine 7; SCYB7; Beta-Thromboglobulin; CTAP3; NAP-2-L1; CXCL7; Small Inducible Cytokine Subfamily B, Member 7; MDGF; Neutrophil-activating Peptide-2; LDGF; Low-Affinity platelet factor I
Species:  
Rat
Source:  
CHO
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Cat. No.: HY-P72676
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPBP; Macrophage-Derived Growth factor; Prev. THBGB1; C-X-C Motif Chemokine 7; SCYB7; Beta-Thromboglobulin; CTAP3; NAP-2-L1; CXCL7; Small Inducible Cytokine Subfamily B, Member 7; MDGF; Neutrophil-activating Peptide-2; LDGF; Low-Affinity platelet factor I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P75699
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPBP; Macrophage-Derived Growth factor; Prev. THBGB1; C-X-C Motif Chemokine 7; SCYB7; Beta-Thromboglobulin; CTAP3; NAP-2-L1; CXCL7; Small Inducible Cytokine Subfamily B, Member 7; MDGF; Neutrophil-activating Peptide-2; LDGF; Low-Affinity platelet factor I
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P75700
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPBP; Macrophage-Derived Growth factor; Prev. THBGB1; C-X-C Motif Chemokine 7; SCYB7; Beta-Thromboglobulin; CTAP3; NAP-2-L1; CXCL7; Small Inducible Cytokine Subfamily B, Member 7; MDGF; Neutrophil-activating Peptide-2; LDGF; Low-Affinity platelet factor I
Species:  
Rat
Source:  
P. pastoris
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Cat. No.: HY-P76854
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPBP; Macrophage-Derived Growth factor; Prev. THBGB1; C-X-C Motif Chemokine 7; SCYB7; Beta-Thromboglobulin; CTAP3; NAP-2-L1; CXCL7; Small Inducible Cytokine Subfamily B, Member 7; MDGF; Neutrophil-activating Peptide-2; LDGF; Low-Affinity platelet factor I
Species:  
Rhesus Macaque Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P76855
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPBP; Macrophage-Derived Growth factor; Prev. THBGB1; C-X-C Motif Chemokine 7; SCYB7; Beta-Thromboglobulin; CTAP3; NAP-2-L1; CXCL7; Small Inducible Cytokine Subfamily B, Member 7; MDGF; Neutrophil-activating Peptide-2; LDGF; Low-Affinity platelet factor I
Species:  
Cynomolgus Rhesus Macaque
Source:  
P. pastoris
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Cat. No.: HY-P700049AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPBP; Macrophage-Derived Growth factor; Prev. THBGB1; C-X-C Motif Chemokine 7; SCYB7; Beta-Thromboglobulin; CTAP3; NAP-2-L1; CXCL7; Small Inducible Cytokine Subfamily B, Member 7; MDGF; Neutrophil-activating Peptide-2; LDGF; Low-Affinity platelet factor I
Species:  
Human
Source:  
E. coli
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