Lp-PLA2-IN-10
Lp-PLA2-IN-10 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-10 has the potential for the research of neurodegenerative-related diseases such as Alzheimer's disease (AD), glaucoma, age-related macular degeneration (AMD), or cardiovascular diseases including atherosclerosis (extracted from patent WO2022001881A1, compound 4).
For research use only. We do not sell to patients.
- CAS No.: 2756855-45-3
- Formula: C21H15F5N4O4
- Molecular Weight:482.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Phospholipase Isoforms
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Biological Activity
Chemical Information
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CAS No. 2756855-45-3
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Molecular Weight 482.36
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Formula C21H15F5N4O4
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SMILES
O=C1N=C(C2=C3N(CCN13)CCO2)OCC4=CC(F)=C(C(F)=C4)OC5=CC(C(F)(F)F)=NC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)