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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
205 Results for "
Calmodulin
" in MedChemExpress (MCE) Product Catalog:
Products (205)
205 Results for "Calmodulin" in MCE Product Catalog:
Cat. No.: HY-137658
CAS No.: 23197-96-8
Synonyms: PTP
Research Areas:
Purine riboside-5'-O-triphosphate, an active metabolite of Nebularine (HY-103694), acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 µM and 28 µM for the human enzyme, respectively. Purine riboside-5'-O-triphosphate also inhibits calmodulin-dependent protein kinase II (CaMKII) with a Ki value of 590 µM .
Cat. No.: HY-137658A
CAS No.: 35892-95-6
Synonyms: PTP tetrasodium
Research Areas:
Purine riboside-5'-O-triphosphate sodium, an active metabolite of Nebularine (HY-103694), acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 µM and 28 µM for the human enzyme, respectively. Purine riboside-5'-O-triphosphate sodium inhibits calmodulin-dependent protein kinase II (CaMKII) with a Ki value of 590 µM .
Cat. No.: HY-P87013
Synonyms: Ca(2+)/Calmodulin-dependent protein kinase phosphatase N antibody; CaMKN antibody; CaMKP-N antibody; CaMKP-nucleus antibody; KIAA1072 antibody; Nuclear Calmodulin dependent protein kinase phosphatase antibody; Partner of PIX 1 antibody; Partner of PIX-alpha antibody; Partner of PIXA antibody; POPX1 antibody; Ca(2+)/Calmodulin-dependent protein kinase phosphatase N antibody; CaMKN antibody; CaMKP-N antibody; CaMKP-nucleus antibody; KIAA1072 antibody; Nuclear Calmodulin dependent protein kinase phosphatase antibody; Partner of PIX 1 antibody; Partner of PIX-alpha antibody; Partner of PIXA antibody; POPX1 antibody; PP2CH antibody; Ppm1e antibody; PPM1E_HUMAN antibody; Protein phosphatase 1E antibody; Protein phosphatase Mg2+/Mn2+ dependent 1E antibody;
Cat. No.: HY-111093
CAS No.: 926319-75-7
Target:
Research Areas:
Protein kinase inhibitor 8 (Compound CK59) is a calmodulin-dependent protein kinase II (CaMKII) inhibitor. By inhibiting the activity of CaMKII, Protein kinase inhibitor 8 can attenuate the cytotoxicity induced by perfluorooctane sulfonic acid (PFOS) and alleviate the downregulation of GLT-1 expression caused by PFOS, thereby reducing neuronal damage. Protein kinase inhibitor 8 may be useful in research related to neurodegenerative diseases .
Cat. No.: HY-P5525
Synonyms: Autocamtide-3 Derived Inhibitory Peptide
Cat. No.: HY-W720917
CAS No.: 41787-69-3
Cat. No.: HY-W181102
CAS No.: 422546-87-0
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
NFAT Inhibitor-2 is a potent inhibitor of calcineurin NFAT signalling. Calcineurin is a serine/threonine protein phosphatase regulated by Ca2+ and calmodulin. NFAT Inhibitor-2 has the potential for the research of inflammatory disease, an autoimmune disorder, a cardiovascular disease, a neurodegenerative disease, a disease occurring with uncontrolled cell proliferation and/or differentiation, an angiogenesis-related disease, an allergy, anaphylaxis and alopecia (extracted from patent WO2016207212A1, compound 17) .
Cat. No.: HY-16129
CAS No.: 565434-85-7
Research Areas:
Cat. No.: HY-16129A
Research Areas:
Cat. No.: HY-B0532AS
CAS No.: 1432064-02-2
Research Areas:
Trifluoperazine dimaleate, an antipsychotic agent, acts by blocking central dopamine receptors. Trifluoperazine dimaleate is a potent α1-adrenergic receptor antagonist. Trifluoperazine dimaleate is a potent NUPR1 inhibitor exerting anticancer activity. Trifluoperazine dimaleate is a calmodulin inhibitor, and also inhibits P-glycoprotein. Trifluoperazine dimaleate can be used for the research of schizophrenia. Trifluoperazine dimaleate acts as a reversible inhibitor of influenza virus morphogenesis .
Cat. No.: HY-B0532AR
CAS No.: 440-17-5
Target:
Reference Standards Dopamine Receptor Adrenergic Receptor CaMK P-glycoprotein Influenza Virus Autophagy
Research Areas:
Trifluoperazine (dihydrochloride) (Standard) is the analytical standard of Trifluoperazine (dihydrochloride). This product is intended for research and analytical applications. Trifluoperazine dihydrochloride, an antipsychotic agent, acts by blocking central dopamine receptors. Trifluoperazine dihydrochloride is a potent α1-adrenergic receptor antagonist. Trifluoperazine dihydrochloride is a potent NUPR1 inhibitor exerting anticancer activity. Trifluoperazine dihydrochloride is a calmodulin inhibitor, and also inhibits P-glycoprotein. Trifluoperazine dihydrochloride can be used for the research of schizophrenia. Trifluoperazine dihydrochloride acts as a reversible inhibitor of influenza virus morphogenesis .
Cat. No.: HY-W030796R
CAS No.: 13794-15-5
Target:
Research Areas:
Trifluoperazine (dihydrochloride) (Standard) is the analytical standard of Trifluoperazine (dihydrochloride). This product is intended for research and analytical applications. Trifluoperazine dihydrochloride, an antipsychotic agent, acts by blocking central dopamine receptors. Trifluoperazine dihydrochloride is a potent α1-adrenergic receptor antagonist. Trifluoperazine dihydrochloride is a potent NUPR1 inhibitor exerting anticancer activity. Trifluoperazine dihydrochloride is a calmodulin inhibitor, and also inhibits P-glycoprotein. Trifluoperazine dihydrochloride can be used for the research of schizophrenia. Trifluoperazine dihydrochloride acts as a reversible inhibitor of influenza virus morphogenesis .
Cat. No.: HY-179016
Research Areas:
Ferroptosis/apoptosis inducer-3 (Compound 34) is a Ferroptosis and Apoptosis inducer. Ferroptosis/apoptosis inducer-3 induces both Ferroptosis and Apoptosis by causing G2/M phase cell cycle arrest, disrupting mitochondrial membrane potentials, promoting lipid peroxidation, and increasing the levels of Ca 2+ and Fe 2+ through the activation of calcium/calmodulin signaling. Ferraplasm/apoptosis inducer-3 shows anticancer effects against cervical cancer, adenocarcinoma, breast cancer, colon cancer, and colorectal carcinoma .
Cat. No.: HY-19805R
CAS No.: 52029-86-4
Target:
Research Areas:
STO-609 (Standard) is the analytical standard of STO-609 (HY-19805). This product is intended for research and analytical applications. STO-609 is a selective and cell-permeable inhibitor of the Ca 2+/calmodulin-dependent protein Kinase Kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 inhibits AMP-activated protein Kinase Kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
