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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
205 Results for "
Calmodulin
" in MedChemExpress (MCE) Product Catalog:
Products (205)
205 Results for "Calmodulin" in MCE Product Catalog:
Target:
Áreas de investigación:
(E)-KN-93 phosphate is a Ca 2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with IC50 values of 9 μM and 3 μM against CaMKIIδMonomer and CaMKIIδDodecamer, respectively. (E)-KN-93 phosphate can be used in research on epilepsy, depression, and arrhythmias. .
Referencia número: HY-130748
No. CAS: 105114-22-5
Target:
Áreas de investigación:
K-252d is an indolocarbazole alkaloid found in Nocardiopsis. It is a PKC inhibitor that inhibits PKC isolated from rat brain (IC50=350 nM). It also inhibits calcium- and calmodulin-dependent phosphodiesterase isolated from bovine heart (IC50=46.2 μM).
Target:
Áreas de investigación:
CaMKIIα-IN-1 (Compound 4d) is an orally active Ca 2+/calmodulin-dependent protein kinase II α (CaMKIIα) inhibitor with a KD of 219 nM for CaMKIIα WT hub. CaMKIIα-IN-1 has good metabolic stability .
Referencia número: HY-P88028
Synonyms: CAMKKB, KIAA0787, CAMKK2, Calcium/Calmodulin-dependent protein kinase kinase 2, CaM-KK 2, CaM-kinase kinase 2, CaMKK 2, Calcium/Calmodulin-dependent protein kinase kinase beta, CaM-KK beta, CaM-kinase kinase beta, CaMKK beta
Referencia número: HY-168905
No. CAS: 2561494-76-4
Target:
Áreas de investigación:
SGC-CAMKK2-1, a chemical probe, is the selective, inhibitor for calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) with an IC50 of 30 nM. SGC-CAMKK2-1 inhibits AMPK phosphorylation in cell C4-2 with an IC50 of 1.6 μM .
Referencia número: HY-P74648
Pureza: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PDE1C; Phosphodiesterase 1C, Calmodulin-Dependent (70kD); Phosphodiesterase 1C; 3',5'-Cyclic-GMP Phosphodiesterase; Hcam3; 3',5'-Cyclic-AMP Phosphodiesterase; Dual Specificity Calcium/Calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1C; Unch
Species:
Human
Source:
Sf9 insect cells
Referencia número: HY-P82599
Synonyms: CAMK2B; CAM2; CAMK2; CAMKB; Calcium/Calmodulin-dependent protein kinase type II subunit beta; CaM kinase II subunit beta; CaMK-II subunit beta; CAMK2G; CAMK; CAMK-II; CAMKG; Calcium/Calmodulin-dependent protein kinase type II subunit gamma
Referencia número: HY-117759
No. CAS: 165659-77-8
Synonyms: KAR-2
Target:
Áreas de investigación:
Deacetoxyvinzolidine (KAR-2) is a bis-indol derivative with high anti-microtubular and anti-tumour activities. Deacetoxyvinzolidine exhibits high affinity for bovine purified brain tubulin (Kd of 3 μM) and inhibits microtubule assembly at a concentration of 10 nM. Deacetoxyvinzolidine does not possess anti-calmodulin activity. Deacetoxyvinzolidine can be used for the study of leukaemia .
Referencia número: HY-P86066
Synonyms: CAMK2B; CAM2; CAMK2; CAMKB; Calcium/Calmodulin-dependent protein kinase type II subunit beta; CaM kinase II subunit beta; CaMK-II subunit beta; CAMK2G; CAMK; CAMK-II; CAMKG; Calcium/Calmodulin-dependent protein kinase type II subunit gamma;
Referencia número: HY-P82599A
Synonyms: CAMK2B; CAM2; CAMK2; CAMKB; Calcium/Calmodulin-dependent protein kinase type II subunit beta; CaM kinase II subunit beta; CaMK-II subunit beta; CAMK2G; CAMK; CAMK-II; CAMKG; Calcium/Calmodulin-dependent protein kinase type II subunit gamma
Referencia número: HY-P810546
Synonyms: CAMK2B; CAM2; CAMK2; CAMKB; Calcium/Calmodulin-dependent protein kinase type II subunit beta; CaM kinase II subunit beta; CaMK-II subunit beta; CAMK2G; CAMK; CAMK-II; CAMKG; Calcium/Calmodulin-dependent protein kinase type II subunit gamma
Referencia número: HY-N18114
No. CAS: 162426-22-4
Category:
Polygonaceae Other Phenylpropanoids Fallopia multiflora (Thunb.) Harald. Phenylpropanoids Plants
Target:
Referencia número: HY-W013857
No. CAS: 125697-93-0
Lavendustin C is a potent Ca 2+ calmodulin-dependent kinase II (CaMK II) inhibitor with an IC50 of 0.2 μM. Lavendustin C inhibits EGFR-associated tyrosine kinase (IC50=0.012 μM) and pp60 c-src(+) kinase (IC50=0.5 μM) .
Referencia número: HY-19805A
No. CAS: 1173022-21-3
Áreas de investigación:
STO-609 acetate is a selective and cell-permeable inhibitor of the Ca 2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 acetate inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
Referencia número: HY-P10367
No. CAS: 518069-98-2
Áreas de investigación:
Referencia número: HY-P704164
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NRGN; Calmodulin-Binding Protein; Neurogranin; Protein Kinase C Substrate; RC3; Hng; Neurogranin (Protein Kinase C Substrate, RC3); Ng
Species:
Human
Source:
E. coli
Target:
Áreas de investigación:
NR162 is a selective CASK (Ca 2+/calmodulin-dependent Ser/Thr kinase) inhibitor with an IC50 of 80 nM and a Kd of 22 nM. NR162 shows about 50-fold selectivity for CASK than TYRO3. NR162 targets the unique GFG motif of CASK and has excellent shape complementarity to the CASK ATP binding pocket. NR162 can be used for the research of neurological diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
