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Cat. No.: HY-19805R

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STO-609 (Standard)

STO-609 (Standard) is the analytical standard of STO-609 (HY-19805). This product is intended for research and analytical applications. STO-609 is a selective and cell-permeable inhibitor of the Ca²⁺/calmodulin-dependent protein K_inase K_inase (CaM-KK), with K_i values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 inhibits AMP-activated protein K_inase K_inase (AMPKK) activity in HeLa cell lysates with an IC₅₀ ~0.02 g/ml.

For research use only. We do not sell to patients.

CAS No.: 52029-86-4
Formula: C₁₉H₁₀N₂O₃
Molecular Weight:314.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

STO-609 (Standard) Chemical Structure

CAS No.: 52029-86-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 52029-86-4
Molecular Weight 314.29
Formula C₁₉H₁₀N₂O₃
SMILES

O=C(C1=C2C3=C(C4=NC5=CC=CC=C5N4C(C3=CC=C2)=O)C=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Tokumitsu H, et al. STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase. J Biol Chem. 2002 May 3;277(18):15813-8. [Content Brief]

[2]. Kukimoto-Niino M, et al. Crystal structure of the Ca²⁺/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609. J Biol Chem. 2011 Jun 24;286(25):22570-9. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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