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(1S,2R)-Milnacipran

" in MedChemExpress (MCE) Product Catalog:

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製品番号 製品名 Target 研究分野 構造式
  • HY-B0168B
    Levomilnacipran hydrochloride
    1 Publications Verification

    (1S,2R)-Milnacipran hydrochloride; F-2695 hydrochloride

    		 Serotonin Transporter Trk Receptor PI3K Akt mTOR P-glycoprotein Neurological Disease Inflammation/Immunology
    Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC50 values of 10.5 nM and 19.0 nM, and Ki values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression .
    Levomilnacipran hydrochloride
  • HY-14794A
    Levomilnacipran

    (1S,2R)-Milnacipran; F2695

    		 Serotonin Transporter Trk Receptor PI3K mTOR P-glycoprotein Akt Neurological Disease Inflammation/Immunology
    Levomilnacipran ((1S,2R)-Milnacipran) is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor, with IC50 values of 10.5 nM and 19.0 nM, and Ki values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression .
    Levomilnacipran
  • HY-14794AS
    Levomilnacipran-d10 hydrochloride

    (1S,2R)-Milnacipran-d10 hydrochloride; F2695-d10 hydrochloride

    		 Isotope-Labeled Compounds Serotonin Transporter Trk Receptor PI3K mTOR P-glycoprotein Akt Neurological Disease Inflammation/Immunology
    Levomilnacipran-d10 ((1S,2R)-Milnacipran-d10) hydrochloride is deuterium labeled Levomilnacipran hydrochloride (HY-B0168B). Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC50 values of 10.5 nM and 19.0 nM, and Ki values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression .
    Levomilnacipran-d10 hydrochloride
  • HY-B0168BS
    Levomilnacipran-d5 hydrochloride

    (1S,2R)-Milnacipran-d5 hydrochloride; F-2695-d5 hydrochloride

    		 Isotope-Labeled Compounds Serotonin Transporter Trk Receptor PI3K Akt mTOR P-glycoprotein Neurological Disease Inflammation/Immunology
    Levomilnacipran-d5 ((1S,2R)-Milnacipran-d5) hydrochloride is deuterium labeled Levomilnacipran hydrochloride (HY-B0168B). Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC50 values of 10.5 nM and 19.0 nM, and Ki values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression .
    Levomilnacipran-d5 hydrochloride

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