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(rel)-Salcolin A

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "(rel)-Salcolin A" in MCE Product Catalog:

(rel)-Salcolin A
(rel)-Salcolin A
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Cat. No.: HY-N16764
CAS No.: 1977557-69-9
Category:  

Flavonoids Flavones Asteraceae Extract Phenols Plants Taraxacum officinale F. H. Wigg.

Target:  

Necroptosis NO Synthase

(rel)-Salcolin A is a flavonoid lignan compound with anticancer, anti-inflammatory, and neuroprotective activities. (rel)-Salcolin A has IC50 values ??of 66.69 μM and 56.12 μM against anaplastic thyroid carcinoma cells (HTH83) and papillary thyroid carcinoma cells (TPC1), respectively. (rel)-Salcolin A also inhibits LPS-induced NO production with an IC50 of 14.65 μM. (rel)-Salcolin A exerts its effects by inducing necroptosis in thyroid cancer cells, inhibiting the production of the inflammatory factor NO, and protecting against glutamate-induced neuronal cell damage, with a neuroprotective E50 of 47.44 μM. (rel)-Salcolin A can be used in research related to thyroid cancer, anti-inflammation, and neuroprotection. (rel)-Salcolin A can be naturally extracted from the leaves of Casearia arborea and the stems of Zea mays (corn) .
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