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Cat. No.: HY-N16764

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(rel)-Salcolin A

(rel)-Salcolin A is a flavonoid lignan compound with anticancer, anti-inflammatory, and neuroprotective activities. (rel)-Salcolin A has IC₅₀ values ??of 66.69 μM and 56.12 μM against anaplastic thyroid carcinoma cells (HTH83) and papillary thyroid carcinoma cells (TPC1), respectively. (rel)-Salcolin A also inhibits LPS-induced NO production with an IC₅₀ of 14.65 μM. (rel)-Salcolin A exerts its effects by inducing necroptosis in thyroid cancer cells, inhibiting the production of the inflammatory factor NO, and protecting against glutamate-induced neuronal cell damage, with a neuroprotective E₅₀ of 47.44 μM. (rel)-Salcolin A can be used in research related to thyroid cancer, anti-inflammation, and neuroprotection. (rel)-Salcolin A can be naturally extracted from the leaves of Casearia arborea and the stems of Zea mays (corn).

For research use only. We do not sell to patients.

CAS No.: 1977557-69-9
Formula: C₂₇H₂₆O₁₁
Molecular Weight:526.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

(rel)-Salcolin A Chemical Structure

CAS No.: 1977557-69-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All NO Synthase Isoforms :

Chemical Information

CAS No. 1977557-69-9
Molecular Weight 526.49
Formula C₂₇H₂₆O₁₁
SMILES

O=C1C2=C(O)C=C(O)C=C2OC(C3=CC(OC)=C(C(OC)=C3)O[C@H](CO)[C@@H](C4=CC(OC)=C(C=C4)O)O)=C1
Structure Classification
- Flavonoids
- Flavones
- Phenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jung YJ, et al. Lignan and flavonoids from the stems of Zea mays and their anti-inflammatory and neuroprotective activities. Arch Pharm Res. 2015 Feb;38(2):178-85. [Content Brief]

[2]. Santos AL, et al. Exploring the Antiproliferative Activity of Flavolignans From the Leaves of Casearia arborea (Salicaceae). Chem Biodivers. 2025 Dec;22(12):e01489. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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