2 Results for "

α-Hydroxyglutaric acid-13C5 disodium

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "α-Hydroxyglutaric acid-13C5 disodium" in MCE Product Catalog:

Cat. No.: HY-113038AS
CAS No.: 2482467-23-0
Purity:  99.80%
Synonyms: 2-Hydroxyglutarate-13C5 disodium; 2-Hydroxyglutaric acid-13C5 disodium; 2-Hydroxypentanedioic acid-13C5 disodium
α-Hydroxyglutaric acid- 13C5 (sodium) is the 13C labeled α-Hydroxyglutaric acid sodium . α-Hydroxyglutaric acid (2-Hydroxyglutarate) sodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid sodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
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Cat. No.: HY-W779800
CAS No.: 1648909-80-1
D-α-Hydroxyglutaric acid- 13C5 disodium is the 13C-labeled D-α-Hydroxyglutaric acid (HY-113038). D-α-Hydroxyglutaric acid ((R)-2-Hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. D-α-Hydroxyglutaric acid increases reactive oxygen species (ROS) production. D-α-Hydroxyglutaric acid binds and inhibits ATP synthase and inhibits mTOR signaling .
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