2 Results for "

11β-Hydroxyprogesterone (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "11β-Hydroxyprogesterone (Standard)" in MCE Product Catalog:

Cat. No.: HY-N2337R
CAS No.: 600-57-7
Synonyms: 11β-Hydroxyprogesterone (Standard)
11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase; also activates human mineralocorticoid receptor in COS-7 cells with an ED50 of 10 nM.
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Cat. No.: HY-B1076R
CAS No.: 2668-66-8
Synonyms: HMS (Standard); 6α-Methyl-11β-Hydroxyprogesterone (Standard)
Research Areas:  

Inflammation/Immunology

Medrysone (Standard) is the analytical standard of Medrysone. This product is intended for research and analytical applications. Medrysone (HMS; 6α-Methyl-11β-hydroxyprogesterone) is a STAT6 modulator and M2 macrophage polarization inducer. Medrysone enhances IL-4-triggered STAT6 activation, upregulates the expression of M2 markers, and promotes the secretion of VEGF and CCL2. Medrysone also enhances the pro-migratory activity of M2-like macrophages toward endothelial cells. By regulating macrophage polarization and related repair pathways, Medrysone significantly promotes corneal wound repair in a rat mechanical injury model. Medrysone can be used for research related to corneal injury .
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